Publications des scientifiques de l'IRD

Pennetier Cédric, Bouraima A., Chandre Fabrice, Piameu M., Etang J., Rossignol M., Sidick I., Zogo B., Lacroix Marie-Noëlle, Yadav R., Pigeon O., Corbel Vincent. (2013). Efficacy of Olyset (R) Plus, a new long-lasting insecticidal net incorporating permethrin and piperonil-butoxide against multi-resistant malaria vectors. Plos One, 8 (10), p. e75134. ISSN 1932-6203.

Titre du document
Efficacy of Olyset (R) Plus, a new long-lasting insecticidal net incorporating permethrin and piperonil-butoxide against multi-resistant malaria vectors
Année de publication
2013
Type de document
Article référencé dans le Web of Science WOS:000325552200012
Auteurs
Pennetier Cédric, Bouraima A., Chandre Fabrice, Piameu M., Etang J., Rossignol M., Sidick I., Zogo B., Lacroix Marie-Noëlle, Yadav R., Pigeon O., Corbel Vincent
Source
Plos One, 2013, 8 (10), p. e75134 ISSN 1932-6203
Due to the rapid extension of pyrethroid resistance in malaria vectors worldwide, manufacturers are developing new vector control tools including insecticide mixtures containing at least two active ingredients with different mode of action as part of insecticide resistance management. Olyset (R) Plus is a new long-lasting insecticidal net (LLIN) incorporating permethrin and a synergist, piperonyl butoxide (PBO), into its fibres in order to counteract metabolic-based pyrethroid resistance of mosquitoes. In this study, we evaluated the efficacy of Olyset (R) Plus both in laboratory and field against susceptible and multi-resistant malaria vectors and compared with Olyset (R) Net, which is a permethrin incorporated into polyethylene net. In laboratory, Olyset (R) Plus performed better than Olyset (R) Net against susceptible Anopheles gambiae strain with a 2-day regeneration time owing to an improved permethrin bleeding rate with the new incorporation technology. It also performed better than Olyset (R) Net against multiple resistant populations of An. gambiae in experimental hut trials in West Africa. Moreover, the present study showed evidence for a benefit of incorporating a synergist, PBO, with a pyrethroid insecticide into mosquito netting. These results need to be further validated in a large-scale field trial to assess the durability and acceptability of this new tool for malaria vector control.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
AFRIQUE DE L'OUEST
Localisation
Fonds IRD [F B010061207]
Identifiant IRD
fdi:010061207
Contact