@article{fdi:010061168,
  title = {{C}hromatin reprogramming during the somatic-to-reproductive cell fate transition in plants},
  author = {{S}he, {W}. {J}. and {G}rimanelli, {D}aniel and {R}utowicz, {K}. and {W}hitehead, {M}. {W}. {J}. and {P}uzio, {M}. and {K}otlinski, {M}. and {J}erzmanowski, {A}. and {B}aroux, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he life cycle of flowering plants is marked by several post-embryonic developmental transitions during which novel cell fates are established. {N}otably, the reproductive lineages are first formed during flower development. {T}he differentiation of spore mother cells, which are destined for meiosis, marks the somatic-to-reproductive fate transition. {M}eiosis entails the formation of the haploid multicellular gametophytes, from which the gametes are derived, and during which epigenetic reprogramming takes place. {H}ere we show that in the {A}rabidopsis female megaspore mother cell ({MMC}), cell fate transition is accompanied by large-scale chromatin reprogramming that is likely to establish an epigenetic and transcriptional status distinct from that of the surrounding somatic niche. {R}eprogramming is characterized by chromatin decondensation, reduction in heterochromatin, depletion of linker histones, changes in core histone variants and in histone modification landscapes. {F}rom the analysis of mutants in which the gametophyte fate is either expressed ectopically or compromised, we infer that chromatin reprogramming in the {MMC} is likely to contribute to establishing postmeiotic competence to the development of the pluripotent gametophyte. {T}hus, as in primordial germ cells of animals, the somatic-to-reproductive cell fate transition in plants entails large-scale epigenetic reprogramming.},
  keywords = {{A}rabidopsis ; {P}lant reproduction ; {M}egaspore mother cell ; {H}eterochromatin ; {C}hromatin modifications ; {H}istone variants},
  booktitle = {},
  journal = {{D}evelopment},
  volume = {140},
  numero = {19},
  pages = {4008--4019},
  ISSN = {0950-1991},
  year = {2013},
  DOI = {10.1242/dev.095034},
  URL = {https://www.documentation.ird.fr/hor/fdi:010061168},
}