@article{fdi:010061165, title = {{A}typical human infections by animal trypanosomes}, author = {{T}ruc, {P}hilippe and {B}uscher, {P}. and {C}uny, {G}{\'e}rard and {G}onzatti, {M}. {I}. and {J}annin, {J}. and {J}oshi, {P}. and {J}uyal, {P}. and {L}un, {Z}. {R}. and {M}attioli, {R}. and {P}ays, {E}. and {S}imarro, {P}. {P}. and {T}eixeira, {M}. {M}. {G}. and {T}ouratier, {L}. and {V}incendeau, {P}. and {D}esquesnes, {M}.}, editor = {}, language = {{ENG}}, abstract = {{T}he two classical forms of human trypanosomoses are sleeping sickness due to {T}rypanosoma brucei gambiense or {T}. brucei rhodesiense, and {C}hagas disease due to {T}. cruzi. {H}owever, a number of atypical human infections caused by other {T}. species (or sub-species) have been reported, namely due to {T}. brucei brucei, {T}. vivax, {T}. congolense, {T}. evansi, {T}. lewisi, and {T}. lewisi-like. {T}hese cases are reviewed here. {S}ome infections were transient in nature, while others required treatments that were successful in most cases, although two cases were fatal. {A} recent case of infection due to {T}. evansi was related to a lack of apolipoprotein {L}-{I}, but {T}. lewisi infections were not related to immunosuppression or specific human genetic profiles. {O}ut of 19 patients, eight were confirmed between 1974 and 2010, thanks to improved molecular techniques. {H}owever, the number of cases of atypical human trypanosomoses might be underestimated. {T}hus, improvement, evaluation of new diagnostic tests, and field investigations are required for detection and confirmation of these atypical cases.}, keywords = {}, booktitle = {}, journal = {{P}los {N}eglected {T}ropical {D}iseases}, volume = {7}, numero = {9}, pages = {e2256}, ISSN = {1935-2735}, year = {2013}, DOI = {10.1371/journal.pntd.0002256}, URL = {https://www.documentation.ird.fr/hor/fdi:010061165}, }