@article{fdi:010060740, title = {{A}nopheles moucheti and {A}nopheles vinckei are candidate vectors of ape {P}lasmodium parasites, including {P}lasmodium praefalciparum in {G}abon}, author = {{P}aupy, {C}hristophe and {M}akanga, {B}. and {O}llomo, {B}. and {R}ahola, {N}il and {D}urand, {P}. and {M}agnus, {J}. and {W}illaume, {E}. and {R}enaud, {F}. and {F}ontenille, {D}idier and {P}rugnolle, {F}ranck}, editor = {}, language = {{ENG}}, abstract = {{D}uring the last four years, knowledge about the diversity of {P}lasmodium species in {A}frican great apes has considerably increased. {S}everal new species were described in chimpanzees and gorillas, and some species that were previously considered as strictly of human interest were found to be infecting {A}frican apes. {T}he description in gorillas of {P}. praefalciparum, the closest relative of {P}. falciparum which is the main malignant agent of human malaria, definitively changed the way we understand the evolution and origin of {P}. falciparum. {T}his parasite is now considered to have appeared recently, following a cross-species transfer from gorillas to humans. {H}owever, the {P}lasmodium vector mosquito species that have served as bridge between these two host species remain unknown. {I}n order to identify the vectors that ensure ape {P}lasmodium transmission and evaluate the risk of transfer of these parasites to humans, we carried out a field study in {G}abon to capture {A}nopheles in areas where wild and semi-wild ape populations live. {W}e collected 1070 {A}nopheles females belonging to 15 species, among which {A}n. carnevalei, {A}n. moucheti and {A}n. marshallii were the most common species. {U}sing mt{DNA}-based {PCR} tools, we discovered that {A}n. moucheti, a major human malaria vector in {C}entral {A}frica, could also ensure the natural transmission of {P}. praefalciparum among great apes. {W}e also showed that, together with {A}n. vinckei, {A}n. moucheti was infected with {P}. vivax-like parasites. {A}n. moucheti constitutes, therefore, a major candidate for the transfer of {P}lasmodium parasites from apes to humans.}, keywords = {{GABON}}, booktitle = {}, journal = {{P}los {O}ne}, volume = {8}, numero = {2}, pages = {e57294}, ISSN = {1932-6203}, year = {2013}, DOI = {10.1371/journal.pone.0057294}, URL = {https://www.documentation.ird.fr/hor/fdi:010060740}, }