@article{fdi:010060598, title = {{E}valuation of the effectiveness of malaria vector control measures in urban settings of {D}akar by a specific {A}nopheles salivary biomarker}, author = {{D}ram{\'e}, {P}apa {M}akhtar and {D}iallo, {A}. and {P}oinsignon, {A}nne and {B}oussari, {O}. and {D}os {S}antos, {S}t{\'e}phanie and {M}achault, {V}. and {L}alou, {R}ichard and {C}orn{\'e}lie, {S}ylvie and {L}e {H}esran, {J}ean-{Y}ves and {R}emou{\'e}, {F}ranck}, editor = {}, language = {{ENG}}, abstract = {{S}tandard entomological methods for evaluating the impact of vector control lack sensitivity in low-malaria-risk areas. {T}he detection of human {I}g{G} specific to {A}nopheles g{SG}6-{P}1 salivary antigen reflects a direct measure of human-vector contact. {T}his study aimed to assess the effectiveness of a range of vector control measures ({VCM}s) in urban settings by using this biomarker approach. {T}he study was conducted from {O}ctober to {D}ecember 2008 on 2,774 residents of 45 districts of urban {D}akar. {I}g{G} responses to g{SG}6-{P}1 and the use of malaria {VCM}s highly varied between districts. {A}t the district level, specific {I}g{G} levels significantly increased with age and decreased with season and with {VCM} use. {T}he use of insecticide-treated nets, by drastically reducing specific {I}g{G} levels, was by far the most efficient {VCM} regardless of age, season or exposure level to mosquito bites. {T}he use of spray bombs was also associated with a significant reduction of specific {I}g{G} levels, whereas the use of mosquito coils or electric fans/air conditioning did not show a significant effect. {H}uman {I}g{G} response to g{SG}6-{P}1 as biomarker of vector exposure represents a reliable alternative for accurately assessing the effectiveness of malaria {VCM} in low-malaria-risk areas. {T}his biomarker tool could be especially relevant for malaria control monitoring and surveillance programmes in low-exposure/low-transmission settings.}, keywords = {{SENEGAL}}, booktitle = {}, journal = {{P}los {O}ne}, volume = {8}, numero = {6}, pages = {e66354}, ISSN = {1932-6203}, year = {2013}, DOI = {10.1371/journal.pone.0066354}, URL = {https://www.documentation.ird.fr/hor/fdi:010060598}, }