Publications des scientifiques de l'IRD

Ali O., Aseffa A., Bedru A., Lemma T., Moti T., Worku A., Xabher H. G., Yamuah L., Boukary R. M., Collard J. M., Dano I. D., Habiboulaye I., Issaka B., Jusot J. F., Ousmane S., Rabe I., Clark T., Mayer L., Gami J. P., Gamougam K., Kodbesse B., Naibei N., Ngadoua C., Mbainadji L., Moto D. D., Narbe M., Toralta J., Berthe A., Keita M., Diallo K., Onwuchekwa U., Sow S. O., Tamboura B., Traore A., Toure A., Amodu M., Beida O., Gadzama G., Omotara B., Sambo Z., Yahya S., Chandramohan D., Greenwood B., Hassan-King M., Manigart O., Nascimento M., Stuart J., Woukeu A., Bai X. L., Borrow R., Findlow H., Avalo S., Bassene H., Diallo A., Dieng M., Doucouré S., Gomis J. F., Ndiaye A., Sokhna Cheikh, Trape Jean-François, Akalifa B., Forgor A., Hodgson A., Osei I., Quaye S., Williams J., Wontuo P., Basta N., Irving T., Trotter C., Bennett J., Hill D., Harrison O., Rebbetts L., Maiden M., Tekletsion Y., Watkins E. (2013). Meningococcal carriage in the African meningitis belt. Tropical Medicine and International Health, 18 (8), p. 968-978. ISSN 1360-2276.

Titre du document
Meningococcal carriage in the African meningitis belt
Année de publication
2013
Type de document
Article référencé dans le Web of Science WOS:000321504000008
Auteurs
Ali O., Aseffa A., Bedru A., Lemma T., Moti T., Worku A., Xabher H. G., Yamuah L., Boukary R. M., Collard J. M., Dano I. D., Habiboulaye I., Issaka B., Jusot J. F., Ousmane S., Rabe I., Clark T., Mayer L., Gami J. P., Gamougam K., Kodbesse B., Naibei N., Ngadoua C., Mbainadji L., Moto D. D., Narbe M., Toralta J., Berthe A., Keita M., Diallo K., Onwuchekwa U., Sow S. O., Tamboura B., Traore A., Toure A., Amodu M., Beida O., Gadzama G., Omotara B., Sambo Z., Yahya S., Chandramohan D., Greenwood B., Hassan-King M., Manigart O., Nascimento M., Stuart J., Woukeu A., Bai X. L., Borrow R., Findlow H., Avalo S., Bassene H., Diallo A., Dieng M., Doucouré S., Gomis J. F., Ndiaye A., Sokhna Cheikh, Trape Jean-François, Akalifa B., Forgor A., Hodgson A., Osei I., Quaye S., Williams J., Wontuo P., Basta N., Irving T., Trotter C., Bennett J., Hill D., Harrison O., Rebbetts L., Maiden M., Tekletsion Y., Watkins E.
Source
Tropical Medicine and International Health, 2013, 18 (8), p. 968-978 ISSN 1360-2276
A meningococcal serogroup A polysaccharide/tetanus toxoid conjugate vaccine (PsA-TT) (MenAfriVac) is being deployed in countries of the African meningitis belt. Experience with other polysaccharide/protein conjugate vaccines has shown that an important part of their success has been their ability to prevent the acquisition of pharyngeal carriage and hence to stop transmission and induce herd immunity. If PsA-TT is to achieve the goal of preventing epidemics, it must be able to prevent the acquisition of pharyngeal carriage as well as invasive meningococcal disease and whether PsA-TT can prevent pharyngeal carriage needs to be determined. To address this issue, a consortium (the African Meningococcal Carriage (MenAfriCar) consortium) was established in 2009 to investigate the pattern of meningococcal carriage in countries of the African meningitis belt prior to and after the introduction of PsA-TT. This article describes how the consortium was established, its objectives and the standardised field and laboratory methods that were used to achieve these objectives. The experience of the MenAfriCar consortium will help in planning future studies on the epidemiology of meningococcal carriage in countries of the African meningitis belt and elsewhere.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
AFRIQUE
Localisation
Fonds IRD [F B010060510]
Identifiant IRD
fdi:010060510
Contact