@article{fdi:010060486,
  title = {{N}on-genetic determinants of mosquito competence for malaria parasites},
  author = {{L}ef{\`e}vre, {T}hierry and {V}antaux, {A}m{\'e}lie and {D}abir{\'e}, {K}. {R}. and {M}ouline, {K}arine and {C}ohuet, {A}nna},
  editor = {},
  language = {{ENG}},
  abstract = {{U}nderstanding how mosquito vectors and malaria parasites interact is of fundamental interest, and it also offers novel perspectives for disease control. {B}oth the genetic and environmental contexts are known to affect the ability of mosquitoes to support malaria development and transmission, i.e., vector competence. {A}lthough the role of environment has long been recognized, much work has focused on host and parasite genetic effects. {H}owever, the last few years have seen a surge of studies revealing a great diversity of ways in which non-genetic factors can interfere with mosquito-{P}lasmodium interactions. {H}ere, we review the current evidence for such environmentally mediated effects, including ambient temperature, mosquito diet, microbial gut flora, and infection history, and we identify additional factors previously overlooked in mosquito-{P}lasmodium interactions. {W}e also discuss epidemiological implications, and the evolutionary consequences for vector immunity and parasite transmission strategies. {F}inally, we propose directions for further research and argue that an improved knowledge of non-genetic influences on mosquito-{P}lasmodium interactions could aid in implementing conventional malaria control measures and contribute to the design of novel strategies.},
  keywords = {},
  booktitle = {},
  journal = {{P}los {P}athogens},
  volume = {9},
  numero = {6},
  pages = {e1003365},
  ISSN = {1553-7374},
  year = {2013},
  DOI = {10.1371/journal.ppat.1003365},
  URL = {https://www.documentation.ird.fr/hor/fdi:010060486},
}