@article{fdi:010060434,
  title = {{A}ssociation of {HLA}-{G} 3 ' untranslated region polymorphisms with antibody response against {P}lasmodium falciparum antigens : preliminary results},
  author = {{S}abbagh, {A}. and {C}ourtin, {D}avid and {M}ilet, {J}acqueline and {M}assaro, {J}. {D}. and {C}astelli, {E}. {C}. and {M}igot {N}abias, {F}lorence and {F}avier, {B}. and {R}ouas-{F}reiss, {N}. and {M}oreau, {P}. and {G}arcia, {A}ndr{\'e} and {D}onadi, {E}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}ost and {P}lasmodium interactions result in highly variable clinical phenotypes, partly explained by the nature and level of anti-malarial antibody response. {H}uman leukocyte antigen ({HLA})-{G} can create a tolerogenic environment, allowing parasites to escape from anti-malarial immunity. {W}e performed a family-based association study encompassing 483 {S}ereer individuals (261 children and their parents), and reported two independent signals at the {HLA}-{G} 3' untranslated region associated with antibody response to specific {P}lasmodium falciparum blood stage antigens, previously associated with malaria protection: (i) +3010{G} together with +3142{C} with total {I}g{G} and {I}g{G}1 against {GLURP} and (ii) +3196{G} with {I}g{G}3 against {MSP}2. {W}hile these results require further investigation, they suggest for the first time a role of {HLA}-{G} in the regulation of humoral immune response in malaria.},
  keywords = {antibody response ; family-based association ; haplotype analysis ; human ; leukocyte antigen-{G} ; malaria ; {P}lasmodium falciparum},
  booktitle = {},
  journal = {{T}issue {A}ntigens},
  volume = {82},
  numero = {1},
  pages = {53--58},
  ISSN = {0001-2815},
  year = {2013},
  DOI = {10.1111/tan.12140},
  URL = {https://www.documentation.ird.fr/hor/fdi:010060434},
}