@article{fdi:010060422,
  title = {{H}ow clonal are {T}rypanosoma and {L}eishmania ?},
  author = {{T}ibayrenc, {M}ichel and {A}yala, {F}. {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he clonal theory of parasitic protozoa has been recently challenged by researchers stating that recombination in {K}inetoplastida is much more frequent than previously believed, or that selfing and homogamy should be distinguished from 'strict' clonality. {T}hese researchers and many others show that the concept of clonality proposed by us is not correctly understood. {A} recapitulation of the clonal theory will thus be addressed herein. {C}omparisons with various other pathogens evidence general features among them and enhance our understanding of {T}rypanosome and {L}eishmania population genetics. {T}he relevance is considerable not only for our knowledge of the basic biology of these organisms but also for applied research: molecular epidemiology (strain-typing), clinical research, vaccine and drug design, and experimental evolution.},
  keywords = {{K}inetoplastida ; clonality ; population genetics ; molecular epidemiology ; linkage disequilibrium ; preponderant clonal evolution ; selfing ; homogamy},
  booktitle = {},
  journal = {{T}rends in {P}arasitology},
  volume = {29},
  numero = {6},
  pages = {264--269},
  ISSN = {1471-4922},
  year = {2013},
  DOI = {10.1016/j.pt.2013.03.007},
  URL = {https://www.documentation.ird.fr/hor/fdi:010060422},
}