@article{fdi:010060284,
  title = {{D}iversity of cultivable fungi associated with {A}ntarctic marine sponges and screening for their antimicrobial, antitumoral and antioxidant potential},
  author = {{H}enriquez, {M}. and {V}ergara, {K}. and {N}orambuena, {J}. and {B}eiza, {A}. and {M}aza, {F}. and {U}billa, {P}. and {A}raya, {I}. and {C}havez, {R}. and {S}an-{M}artın, {A}. and {D}arias, {J}. and {D}arias, {M}aria {J}ose and {V}aca, {I}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he diversity of sponge-associated fungi has been poorly investigated in remote geographical areas like {A}ntarctica. {I}n this study, 101 phenotypically different fungal isolates were obtained from 11 sponge samples collected in {K}ing {G}eorge {I}sland, {A}ntarctica. {T}he analysis of {ITS} sequences revealed that they belong to the phylum {A}scomycota. {S}ixty-five isolates belong to the genera {G}eomyces, {P}enicillium, {E}picoccum, {P}seudeurotium, {T}helebolus, {C}ladosporium, {A}spergillus, {A}ureobasidium, {P}homa, and {T}richocladium but 36 isolates could not be identified at genus level. {I}n order to estimate the potential of these isolates as producers of interesting bioactivities, antimicrobial, antitumoral and antioxidant activities of fungal culture extracts were assayed. {A}round 51 % of the extracts, mainly from the genus {G}eomyces and non identified relatives, showed antimicrobial activity against some of the bacteria tested. {O}n the other hand, around 42 % of the extracts showed potent antitumoral activity, {G}eomyces sp. having the best performance. {F}inally, the potential of the isolated fungi as producers of antioxidant activity seems to be moderate. {O}ur results suggest that fungi associated with {A}ntarctic sponges, particularly {G}eomyces, would be valuable sources of antimicrobial and antitumoral compounds. {T}o our knowledge, this is the first report describing the biodiversity and the metabolic potential of fungi associated with {A}ntarctic marine sponges.},
  keywords = {{SYMBIOSE} ; {ALGUE} {MARINE} ; {CHAMPIGNON} ; {MICROORGANISME} ; {ACTIVITE} {BIOLOGIQUE} ; {PHENOTYPE} ; {PHYLOGENIE} ; {ACTION} {ANTITUMORALE} ; {ANTIOXYDANT} ; {ACTIVITE} {ANTIBACTERIENNE} ; {OCEAN} {ANTARCTIQUE} ; {ROI} {GEORGE} {ILE}},
  booktitle = {},
  journal = {{W}orld {J}ournal of {M}icrobiology and {B}iotechnology},
  volume = {30},
  numero = {1},
  pages = {65--76},
  ISSN = {0959-3993},
  year = {2014},
  DOI = {10.1007/s11274-013-1418-x},
  URL = {https://www.documentation.ird.fr/hor/fdi:010060284},
}