Trape Jean-François, Diatta G., Arnathau C., Bitham I., Sarih M., Belghyti D., Bouattour A., Elguero Eric, Vial L., Mane Y., Baldé C., Prugnolle Franck, Chauvancy Gilles, Mahé Gil, Granjon Laurent, Duplantier Jean-Marc, Durand P., Renaud F. (2013). The epidemiology and geographic distribution of relapsing fever Borreliosis in West and North Africa, with a review of the Ornithodoros erraticus Complex (Acari: Ixodida). PloS One, 8 (11), e78473 (19 p.). ISSN 1932-6203.
Titre du document
The epidemiology and geographic distribution of relapsing fever Borreliosis in West and North Africa, with a review of the Ornithodoros erraticus Complex (Acari: Ixodida)
Année de publication
2013
Auteurs
Trape Jean-François, Diatta G., Arnathau C., Bitham I., Sarih M., Belghyti D., Bouattour A., Elguero Eric, Vial L., Mane Y., Baldé C., Prugnolle Franck, Chauvancy Gilles, Mahé Gil, Granjon Laurent, Duplantier Jean-Marc, Durand P., Renaud F.
Source
PloS One, 2013,
8 (11), e78473 (19 p.) ISSN 1932-6203
Background: Relapsing fever is the most frequent bacterial disease in Africa. Four main vector / pathogen complexes are classically recognized, with the louse Pediculus humanus acting as vector for B. recurrentis and the soft ticks Ornithodoros sonrai, O. erraticus and O. moubata acting as vectors for Borrelia crocidurae, B. hispanica and B. duttonii, respectively. Our aim was to investigate the epidemiology of the disease in West, North and Central Africa. Methods And Findings: From 2002 to 2012, we conducted field surveys in 17 African countries and in Spain. We investigated the occurrence of Ornithodoros ticks in rodent burrows in 282 study sites. We collected 1,629 small mammals that may act as reservoir for Borrelia infections. Using molecular methods we studied genetic diversity among Ornithodoros ticks and Borrelia infections in ticks and small mammals. Of 9,870 burrows investigated, 1,196 (12.1%) were inhabited by Ornithodoros ticks. In West Africa, the southern and eastern limits of the vectors and Borrelia infections in ticks and small mammals were 13°N and 01°E, respectively. Molecular studies revealed the occurrence of nine different Ornithodoros species, including five species new for science, with six of them harboring Borrelia infections. Only B. crocidurae was found in West Africa and three Borrelia species were identified in North Africa: B. crocidurae, B. hispanica, and B. merionesi. Conclusions: Borrelia Spirochetes responsible for relapsing fever in humans are highly prevalent both in Ornithodoros ticks and small mammals in North and West Africa but Ornithodoros ticks seem absent south of 13°N and small mammals are not infected in these regions. The number of Ornithodoros species acting as vector of relapsing fever is much higher than previously known.
Plan de classement
Tiques [052TIAC01]
Descripteurs
INFECTION ; BACTERIE ; VECTEUR ; EPIDEMIOLOGIE ; REPARTITION GEOGRAPHIQUE ; CAPTURE ; DIAGNOSTIC ; BIOLOGIE MOLECULAIRE ; PHYLOGENIE ; ETUDE COMPARATIVE ; BORRELIOSE ; TIQUE ; NOMENCLATURE ; RONGEUR ; DETECTION ; DIVERSITE GENETIQUE ; TECHNIQUE PCR
Description Géographique
AFRIQUE ; AFRIQUE DE L'OUEST ; AFRIQUE DU NORD ; AFRIQUE CENTRALE
Localisation
Fonds IRD [F B010060155]
Identifiant IRD
fdi:010060155
