@article{fdi:010056917, title = {{H}omophymines {B}-{E} and {A}1-{E}1, a family of bioactive cyclodepsipeptides from the sponge {H}omophymia sp.}, author = {{Z}ampella, {A}. and {S}epe, {V}. and {B}ellotta, {F}. and {L}uciano, {P}. and {D}'{A}uria, {M}. {V}. and {C}resteil, {T}. and {D}ebitus, {C}{\'e}cile and {P}etek, {S}ylvain and {P}oupat, {C}. and {A}hond, {A}.}, editor = {}, language = {{ENG}}, abstract = {{N}ine new cyclodepsipeptides, homophymines {B}-{E} (2-5) and {A}1-{E}1 (1a-5a), were isolated from the polar extracts of the sponge {H}omophymia sp. {T}he new structures, featuring new polyketide-derived end groups, were determined by interpretation of {NMR} and {MS} data. {T}he configurations of the new end groups was secured by the application of {J}-based configurational analysis. {H}omophymines displayed very potent antiproliferative activity ({IC}50 in the n{M} range) against a panel of human cancer cell lines.}, keywords = {}, booktitle = {}, journal = {{O}rganic and {B}iomolecular {C}hemistry}, volume = {7}, numero = {19}, pages = {4037--4044}, ISSN = {1477-0520}, year = {2009}, DOI = {10.1039/b910015f}, URL = {https://www.documentation.ird.fr/hor/fdi:010056917}, }