@article{fdi:010055843, title = {{T}riterpene saponins from {A}ntonia ovata leaves}, author = {{M}agid, {A}. {A}. and {L}alun, {N}. and {L}ong, {C}. and {B}orie, {N}. and {B}obichon, {H}. and {M}oretti, {C}hristian and {L}avaud, {C}.}, editor = {}, language = {{ENG}}, abstract = {{S}ix pentacyclic triterpenoid saponins, named antoniosides {E}-{J} along with two known alkaloids, were isolated from the leaves of {A}ntonia ovata. {T}heir structures were determined by the extensive use of 1{D} and 2{D}-{NMR} experiments along with {HRESIMS} analysis and acid hydrolysis. {A}ll isolated saponins contained the same pentasaccharide chain: 3-{O}-[beta-{D}-glucopyranosyl-(1 -> 2)]-[beta-{D}-glucopyranosyl-(1 -> 4)]-[beta-{D}-glucopyranosyl-(1 -> 3)-alpha-{L}-arabinopyranosyl(1 -> 6)]-beta-{D}-glucopyranoside, linked at {C}-3 of esterified derivatives of polyhydroxyoleanene triterpenoids (theasapogenol {A} and 15 alpha-hydroxy-theasapogenol {A}). {I}solated compounds were evaluated for their cytotoxic activity against {KB} cell line by a {WST}-1 assay, and the {IC}50 values ranged from 3.3 to 5.3 mu {M}.}, keywords = {{A}ntonia ovata ; {L}oganiaceae ; {T}riterpenoid saponins ; {T}heasapogenol {A} ; 15 alpha-{H}ydroxy-theasapogenol {A} ; {C}ytotoxic activity}, booktitle = {}, journal = {{P}hytochemistry}, volume = {77}, numero = {}, pages = {268--274}, ISSN = {0031-9422}, year = {2012}, DOI = {10.1016/j.phytochem.2012.01.025}, URL = {https://www.documentation.ird.fr/hor/fdi:010055843}, }