@article{fdi:010055740,
  title = {{P}lasmodium falciparum produce lower infection intensities in local versus foreign {A}nopheles gambiae populations},
  author = {{H}arris, {C}aroline and {M}orlais, {I}sabelle and {C}hurcher, {T}. {S}. and {A}wono-{A}mbene, {P}. and {G}ouagna, {L}ouis-{C}l{\'e}ment and {D}abire, {R}. {K}. and {F}ontenille, {D}idier and {C}ohuet, {A}nna},
  editor = {},
  language = {{ENG}},
  abstract = {{B}oth {P}lasmodium falciparum and {A}nopheles gambiae show great diversity in {A}frica, in their own genetic makeup and population dynamics. {T}he genetics of the individual mosquito and parasite are known to play a role in determining the outcome of infection in the vector, but whether differences in infection phenotype vary between populations remains to be investigated. {H}ere we established two {A}. gambiae s.s. {M} molecular form colonies from {C}ameroon and {B}urkina {F}aso, representing a local and a foreign population for each of the geographical sites. {E}xperimental infections of both colonies were conducted in {C}ameroon and {B}urkina {F}aso using local wild {P}. falciparum, giving a sympatric and allopatric vector-parasite combination in each site. {I}nfection phenotype was determined in terms of oocyst prevalence and intensity for at least nine infections for each vector-parasite combination. {S}ympatric infections were found to produce 25% fewer oocysts per midgut than allopatric infections, while prevalence was not affected by local/foreign interactions. {T}he reduction in oocyst numbers in sympatric couples may be the result of evolutionary processes where the mosquito populations have locally adapted to their parasite populations. {F}uture research on vector-parasite interactions must take into account the geographic scale of adaptation revealed here by conducting experiments in natural sympatric populations to give epidemiologically meaningful results.},
  keywords = {{BURKINA} {FASO} ; {CAMEROUN}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {7},
  numero = {1},
  pages = {e30849},
  ISSN = {1932-6203},
  year = {2012},
  DOI = {10.1371/journal.pone.0030849},
  URL = {https://www.documentation.ird.fr/hor/fdi:010055740},
}