@article{fdi:010053695,
  title = {{W}orldwide patterns of genetic differentiation imply multiple 'domestications' of {A}edes aegypti, a major vector of human diseases},
  author = {{B}rown, {J}. {E}. and {M}c{B}ride, {C}. {S}. and {J}ohnson, {P}. and {R}itchie, {S}. and {P}aupy, {C}hristophe and {B}ossin, {H}. and {L}utomiah, {J}. and {F}ernandez-{S}alas, {I}. and {P}onlawat, {A}. and {C}ornel, {A}. {J}. and {B}lack, {W}. {C}. and {G}orrochotegui-{E}scalante, {N}. and {U}rdaneta-{M}arquez, {L}. and {S}ylla, {M}. and {S}lotman, {M}. and {M}urray, {K}. {O}. and {W}alker, {C}. and {P}owell, {J}. {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{U}nderstanding the processes by which species colonize and adapt to human habitats is particularly important in the case of disease-vectoring arthropods. {T}he mosquito species {A}edes aegypti, a major vector of dengue and yellow fever viruses, probably originated as a wild, zoophilic species in sub-{S}aharan {A}frica, where some populations still breed in tree holes in forested habitats. {M}any populations of the species, however, have evolved to thrive in human habitats and to bite humans. {T}his includes some populations within {A}frica as well as almost all those outside {A}frica. {I}t is not clear whether all domestic populations are genetically related and represent a single 'domestication' event, or whether association with human habitats has developed multiple times independently within the species. {T}o test the hypotheses above, we screened 24 worldwide population samples of {A}e. aegypti at 12 polymorphic microsatellite loci. {W}e identified two distinct genetic clusters: one included all domestic populations outside of {A}frica and the other included both domestic and forest populations within {A}frica. {T}his suggests that human association in {A}frica occurred independently from that in domestic populations across the rest of the world. {A}dditionally, measures of genetic diversity support {A}e. aegypti in {A}frica as the ancestral form of the species. {I}ndividuals from domestic populations outside {A}frica can reliably be assigned back to their population of origin, which will help determine the origins of new introductions of {A}e. aegypti.},
  keywords = {{A}edes aegypti aegypti ; {A}edes aegypti formosus ; human habitats ; microsatellites ; evolution ; mosquito genetics},
  booktitle = {},
  journal = {{P}roceedings of the {R}oyal {S}ociety {B}. {B}iological {S}ciences},
  volume = {278},
  numero = {1717},
  pages = {2446--2454},
  ISSN = {0962-8452},
  year = {2011},
  DOI = {10.1098/rspb.2010.2469},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053695},
}