@article{fdi:010053379,
  title = {{M}olecular survey of rodent-borne {T}rypanosoma in {N}iger with special emphasis on {T}. lewisi imported by invasive black rats},
  author = {{D}obigny, {G}authier and {P}oirier, {P}. and {H}ima, {K}armadine and {C}abaret, {O}. and {G}authier, {P}hilippe and {T}atard, {C}. and {C}osta, {J}. {M}. and {B}retagne, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}nvading rodent species can harbor parasites with potential transmission to native rodents and/or humans. {T}o investigate trypanosomes prevalence in rodents, the spleen of 76 rodents from {N}iger identified by their karyotype was used as a {DNA} source for {T}rypanosoma detection using a newly developed q{PCR} assay. {O}f the invasive black rat, {R}attus rattus, 71% (10/14) were {PCR} positive as well as 6% (4/62) of native {A}frican rodents. {S}equences of similar to 400 bp of the {SSU} r{DNA} gene identified phylogenetically close {T}rypanosoma lineages. {T}rypanosoma lewisi was present in all positive black rats and the sequences displayed 100% similarity with {T}. lewisi-infected humans in {S}enegal. {T}. lewisi was also detected in one {A}comys johannis, suggesting a possible transmission to native species. {I}n addition to improved knowledge of {T}rypanosoma diversity in rodents, our data underscore the introduction of the potentially pathogenic {T}. lewisi kinetoplastid through the human-mediated invasion of black rats all over {W}est {A}frica.},
  keywords = {{Z}oonotic emerging disease ; {B}iological invasion ; {R}attus rattus ; {A}frica ; {Q}uantitative real-time {PCR}},
  booktitle = {},
  journal = {{A}cta {T}ropica},
  volume = {117},
  numero = {3},
  pages = {183--188},
  ISSN = {0001-706{X}},
  year = {2011},
  DOI = {10.1016/j.actatropica.2010.11.004},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053379},
}