@article{fdi:010052999,
  title = {{H}andgrip strength : indications of paternal inheritance in three {E}uropean regions},
  author = {{C}ournil, {A}mandine and {J}eune, {B}. and {S}kytthe, {A}. and {G}ampe, {J}. and {P}assarino, {G}. and {R}obine, {J}. {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground. {H}andgrip strength is an indicator of overall muscle strength. {P}oor handgrip strength is a risk factor for disability and mortality. {W}e aimed to investigate the pattern of inheritance of handgrip strength in a sample of parent-offspring pairs from three different {E}uropean regions in {D}enmark, {F}rance, and {I}taly. {M}ethods. {I}n this substudy of the {E}uropean {C}hallenge for {H}ealthy {A}ging study, handgrip strength was measured in 290 subjects aged 90 years and older and in one of their offspring. {R}esults. {W}hen all pairs were considered together, parental and offspring handgrip strength were weakly correlated (r = .16; p < .01). {H}owever, paternal-offspring correlation was significantly higher than maternal-offspring correlation (r = .26; confidence interval [{CI}]: 0.11-0.41 versus r = .03; {CI}: -0.14 to 0.19; p = .04). {T}his difference was particularly marked for daughters (r = -.07; {CI}: -0.29 to 0.16 for mother-daughter correlation versus r = .31; {CI}: 0.11-0.49 for father-daughter; p = .01) compared with sons (r = .12; {CI}: -0.13 to 0.36 for mother-son correlation versus r = .25; {CI}: 0.00-0.46 for father-son; p = .47). {F}ather-daughter correlation remained higher than mother-daughter when analyses were performed with 144 nondependent parents (r = .32; {CI}: 0.04; 0.55 versus r = -.25; {CI}: -0.61 to 0.21; p = .03). {T}hese results were similarly observed in the three regions of the study, where mean levels of handgrip strength strongly differed. {C}onclusions. {I}t suggests that age-related effects on functional health among women could be mediated more through the paternal line than the maternal.},
  keywords = {{H}andgrip strength ; {P}aternal inheritance ; familial transmission ; {C}entenarians ; {L}ongevity ; {DANEMARK} ; {FRANCE} ; {ITALIE}},
  booktitle = {},
  journal = {{J}ournals of {G}erontology {S}eries a - {B}iological {S}ciences and {M}edical {S}ciences},
  volume = {65},
  numero = {10},
  pages = {1101--1106},
  ISSN = {1079-5006},
  year = {2010},
  DOI = {10.1093/gerona/glq098},
  URL = {https://www.documentation.ird.fr/hor/fdi:010052999},
}