@article{fdi:010049718, title = {{I}nsecticide resistance of {T}riatoma infestans ({H}emiptera, {R}eduviidae) vector of {C}hagas disease in {B}olivia}, author = {{L}ardeux, {F}r{\'e}d{\'e}ric and {D}epick{\`e}re, {S}t{\'e}phanie and {D}uchon, {S}t{\'e}phane and {C}havez, {T}.}, editor = {}, language = {{ENG}}, abstract = {{P}>{O}bjective {T}o define the insecticide resistance status of {T}riatoma infestans to deltamethrin (pyrethroid), malathion (organophosphate) and bendiocarb (carbamate) in {B}olivia. {M}ethods {F}ifty populations of {T}. infestans were sampled in {B}olivian human dwellings. {Q}uantal response data were obtained by topical applications of 0.2 mu l of insecticide-acetone solutions on nymphs {N}1 of the {F}1 generations. {F}or most populations, dose-mortality relationships and resistance ratios ({RR}) were analysed. {D}iscriminating concentrations were established for each insecticide with a susceptible reference strain and used on the other field populations. {A} tarsal-contact diagnostic test using insecticide impregnated papers was designed to rapidly identify deltamethrin-resistant populations in the field. {R}esults {D}iscriminating concentrations for topical applications were 5, 70 and 120 ng active ingredient per insect for deltamethrin, bendiocarb and malathion, respectively. {T}he diagnostic concentration for deltamethrin was 0.30% for the 1-h exposure by tarsal contact. {A}ll populations sampled in human dwellings exhibited significant levels of resistance to deltamethrin, from 6 to 491 and varied among regions. {R}esistant populations did not recover complete susceptibility to deltamethrin when the synergist piperonyl butoxide ({PBO}) was used. {N}one of the sampled populations exhibited significant resistance to bendiocarb (all {RR}50 < 1.8) or malathion (all {RR}50 < 2.2). {C}onclusion {I}n {B}olivia, most 'domestic'{T}. infestans populations are resistant to deltamethrin. {B}ecause insecticide vector control is the only selection pressure, resistance likely originates from it. {S}witching from pyrethroids to organophosphates or carbamates could be a short-term solution to control this vector, but other alternative integrated control strategies should also be considered in the long term.}, keywords = {{T}riatoma infestans ; insecticide ; resistance ; {B}olivia ; {T}riatoma ; infestans ; insecticide ; resistance ; {B}olivie ; {T}riatoma infestans ; insecticida ; resistencia ; {B}olivia ; {BOLIVIE}}, booktitle = {}, journal = {{T}ropical {M}edicine and {I}nternational {H}ealth}, volume = {15}, numero = {9}, pages = {1037--1048}, ISSN = {1360-2276}, year = {2010}, DOI = {10.1111/j.1365-3156.2010.02573.x}, URL = {https://www.documentation.ird.fr/hor/fdi:010049718}, }