@article{fdi:010049393,
  title = {{C}ytotoxic triterpenoid saponins from the stem bark of {A}ntonia ovata},
  author = {{M}agid, {A}. {A}. and {B}obichon, {H}. and {B}orie, {N}. and {L}alun, {N}. and {L}ong, {C}. and {M}oretti, {C}hristian and {L}avaud, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{P}hytochemical investigation of the {M}e{OH} extract of the stem bark of {A}ntonia ovata led to the isolation of four triterpenoid saponins, along with eleven known {C}ompounds {T}heir structures were established by extensive 1{D} and 2{D} {NMR}, as well as {HR}-{MS} analysis and acid hydrolysis {A}ll isolated saponins contained the same tetrasaccharide chain {O}-beta-{D}-xylopyranosyl-(1 -> 2)-{O}-beta-{D}-glucopyranosyl-(1 -> 3)-{O}-[beta-{D}-glucopyranosyl-(1 -> 2)]-beta-{D}-glucuropyranoside linked to {C}-3 of esterified derivatives of {R}-1-barrigenol. {A}(1)-barrigenol, barringtogenol {C}, or camelliagenin {B}iological evaluation of the {C}ompounds against {KB} cell line revealed a potent cytotoxic activity with {IC}50 {V}alues ranging from 3 1 to 6 6 mu {M}. {T}he known compounds were found to be inactive at 10 mu g/ml concentration.},
  keywords = {{A}ntonia ovata ; {L}oganiaceae ; {T}riterpenoid saponins ; {R}-1-barrigenol ; {A}(1)-barrigenol ; {B}arringtogenol {C} ; {C}amelliagenin ; {C}ytotoxic activity},
  booktitle = {},
  journal = {{P}hytochemistry},
  volume = {71},
  numero = {4},
  pages = {429--434},
  ISSN = {0031-9422},
  year = {2010},
  DOI = {10.1016/j.phytochem.2009.11.007},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049393},
}