Ghigo E., Pretat L., Desnues B., Capo C., Raoult Didier, Mege J. L. (2009). Intracellular life of Coxiella burnetii in acrophages : an update. Rickettsiology and Rickettsial Diseases, 1166, p. 55-66. ISSN 0077-8923.
Titre du document
Intracellular life of Coxiella burnetii in acrophages : an update
Ghigo E., Pretat L., Desnues B., Capo C., Raoult Didier, Mege J. L.
Source
Rickettsiology and Rickettsial Diseases, 2009,
1166, p. 55-66 ISSN 0077-8923
Coxiella burnetii, the agent of Q fever, is an obligate intracellular bacterium that is considered a potential biological weapon of category B. C. burnetii survives within myeloid cells by subverting receptor-mediated phagocytosis and preventing phagosome maturation. The intracellular fate of C. burnetii also depends on the functional state of myeloid cells. This review describes the mechanisms used by C. burnetii to circumvent uptake and trafficking events, and the role of cytokines on C. burnetii survival in myeloid cells.
