@article{fdi:010044296, title = {{F}i{\`e}vre {Q} : actualit{\'e}s diagnostiques et th{\'e}rapeutiques = {Q} fever : current diagnosis and treatment options}, author = {{M}illion, {M}. and {L}epidi, {H}. and {R}aoult, {D}idier}, abstract = {{Q} fever is a zoonotic disease caused by the ubiquitous pathogen {C}oxiella burnetii responsible for acute and chronic clinical manifestations. {I}ts geographically heterogeneous prevalence seems mainly related to the clinician interest and the availability of a reference center. {I}ts polymorphic clinical expression imposes reference to diagnosis in presence of pneumonia, hepatitis. prolonged fever or endocarditis with no proof of its etiology. {T}he diagnosis is mainly serological. {I}f acute {Q} fever is most often benign, endocarditis is constantly fatal {W}ithout treatment. {T}he treatment is effective and well tolerated, but must be adapted to the acute or chronic pattern, the presence of a heart valve disease, an aneurysm or a vascular prosthesis, an immunodeficiency and the specific problem of pregnancy.}, keywords = {{Q} fevers ; {C}oxiella burnetii ; {D}oxycyclinc ; {E}ndocarditis ; {H}ydroxychloroquine}, journal = {{M}{\'e}decine et {M}aladies {I}nfectieuses}, volume = {39}, numero = {2}, pages = {82--94}, ISSN = {0399-077{X}}, year = {2009}, DOI = {10.1016/j.medmal.2008.07.008}, URL = {http://www.documentation.ird.fr/hor/fdi:010044296}, }