%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Kouokam, E. %A Auger, Pierre %A Hbid, H. %A Tchuente, Maurice %T Effect of the number of patches in a multi-patch SIRS model with fast migration on the basic reproduction rate %D 2008 %L fdi:010042615 %G ENG %J Acta Biotheoretica %@ 0001-5342 %K SIRS model ; two patch system ; linear chain of patches ; fast migration ; aggregation of variables ; basic reproduction rate ; individual based model ; multi agent simulations %M CC:0002563379-0005 %N 1-2 %P 75-86 %R 10.1007/s10441-008-9036-y %U https://www.documentation.ird.fr/hor/fdi:010042615 %> https://www.documentation.ird.fr/intranet/publi/2008/06/010042615.pdf %V 56 %W Horizon (IRD) %X We consider a two-patch epidemiological system where individuals can move from one patch to another, and local interactions between the individuals within a patch are governed by the classical SIRS model. When the time-scale associated with migration is much smaller than the time-scale associated with infection, aggregation methods can be used to simplify the initial complete model formulated as a system of ordinary differential equations. Analysis of the aggregated model then shows that the two-patch basic reproduction rate is smaller than the 1 patch one. We extend this result to a linear chain of P patches (P > 2). These results are illustrated by some examples for which numerical integration of the system of ordinary differential equations is performed. Simulations of an individual based model implemented with a multi-agent system are also carried out. %$ 050 ; 020