@article{fdi:010042531,
  title = {{A}ntibiotic-resistant soil bacteria in transgenic plant fields},
  author = {{D}emaneche, {S}. and {S}anguin, {H}. and {P}ote, {J}. and {N}avarro, {E}lisabeth and {B}ernillon, {D}. and {M}avingui, {P}. and {W}ildi, {W}. and {V}ogel, {T}. {M}. and {S}imonet, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{U}nderstanding the prevalence and polymorphism of antibiotic resistance genes in soil bacteria and their potential to be transferred horizontally is required to evaluate the likelihood and ecological (and possibly clinical) consequences of the transfer of these genes from transgenic plants to soil bacteria. {I}n this study, we combined culture-dependent and -independent approaches to study the prevalence and diversity of bla genes in soil bacteria and the potential impact that a 110-successive-year culture of the transgenic {B}t176 corn, which has a b/a{TEM} marker gene, could have had on the soil bacterial community. {T}he bla gene encoding resistance to ampicillin belongs to the beta-lactam antibiotic family, which is widely used in medicine but is readily compromised by bacterial antibiotic resistance. {O}ur results indicate that soil bacteria are naturally resistant to a broad spectrum of beta-lactam antibiotics, including the third cephalosporin generation, which has a slightly stronger discriminating effect on soil isolates than other cephalosporins. {T}hese high resistance levels for a wide range of antibiotics are partly due to the polymorphism of bla genes, which occur frequently among soil bacteria. {T}he b/a{TEM}1 16 gene of the transgenic corn {B}t176 investigated here is among those frequently found, thus reducing any risk of introducing a new bacterial resistance trait from the transgenic material. in addition, no significant differences were observed in bacterial antibiotic-resistance levels between transgenic and nontransgenic corn fields, although the bacterial populations were different.},
  keywords = {antibiotic resistance ; {GMO} ; {HGT}},
  booktitle = {},
  journal = {{P}roceedings of the {N}ational {A}cademy of {S}ciences of the {U}nited {S}tates of {A}merica},
  volume = {105},
  numero = {10},
  pages = {3957--3962},
  ISSN = {0027-8424},
  year = {2008},
  DOI = {10.1073/pnas.0800072105},
  URL = {https://www.documentation.ird.fr/hor/fdi:010042531},
}