@article{fdi:010040733,
  title = {{A}pplying population-genetic models in theoretical evolutionary epidemiology},
  author = {{D}ay, {T}. and {G}andon, {S}ylvain},
  abstract = {{M}uch of the existing theory for the evolutionary biology of infectious diseases uses an invasion analysis approach. {I}n this {I}deas and {P}erspectives article, we suggest that techniques from theoretical population genetics can also be profitably used to study the evolutionary epidemiology of infectious diseases. {W}e highlight four ways in which population-genetic models provide benefits beyond those provided by most invasion analyses: (i) they can make predictions about the rate of pathogen evolution; (ii) they explicitly draw out the mechanistic way in which the epidemiological dynamics feed into evolutionary change, and thereby provide new insights into pathogen evolution; (iii) they can make predictions about the evolutionary consequences of non-equilibrium epidemiological dynamics; (iv) they can readily incorporate the effects of multiple host dynamics, and thereby account for phenomena such as immunological history and/or host co-evolution.},
  keywords = {antigenic evolution ; drug resistance ; epidemiology ; infectious diseases ; parasite ; pathogen ; virulence},
  journal = {{E}cology {L}etters},
  volume = {10},
  numero = {10},
  pages = {876--888},
  ISSN = {1461-023{X}},
  year = {2007},
  DOI = {10.1111/j.1461-0248.2007.01091.x},
  URL = {http://www.documentation.ird.fr/hor/fdi:010040733},
}