@techreport{fdi:010015987,
  title = {{E}pidemiology of filovirus infections in the {R}{\'e}publique {C}entrafricaine : a risk study associated with subsistence activities : final report},
  author = {{G}onzalez, {J}ean-{P}aul},
  editor = {{G}onzalez, {J}ean-{P}aul},
  language = {{ENG}},
  abstract = {{W}ith the natural history of the #{F}ilovirus$ family seemingly unknown, filovirus ecology and natural history are still a rudimentary field of research. {W}hen the present project started, monthes before the dramatic and well publicized {K}ikwit outbreak, filovirus were not of any acuality and our group was one of the few to maintain a filovirus specific field research activity. {I}n order to investigate the maintenance cycle of filovirus in {C}entral {A}frica, a study was conducted within the rain forest of the {R}{\'e}publique {C}entrafricaine ({RCA}). {A}n epidemiological study was directed to determine the frequency and distribution of filovirus seroprevalence in a selected human population. {U}sing an {ELISA} test, serum samples from pygmy and non-pygmy populations were tested for {E}bola-{Z}a{\¨ie}re and {M}arburg virus reacting antibodies. {P}ositive sera for filovirus were found in all study groups. {W}ithin the {L}obaye district, {P}ygmies appeared to have a higher seroprevalence against {E}bola-{Z}a{\¨ie}re (12.8%) and {M}arburg (4.36%) virus antigens than non-pygmies (respectively 4.3% and 0.0% seropositivity). {P}ygmy females as an higher {E}bola seroprevalence than males. {I}n contrast, {M}arburg antibody reacting sera were detected more frequently in male (7.6%) than female (1.9%) pygmies. {M}oreover preliminary retrospective studies done of the wet and dry savannah showed a significantly (p<0.04) higher seroprevalence against {M}arburg virus (>11%) than the one observed in the forested area (<4%). {D}uring our study, a temporal increase of {E}bola seroprevalence was observed within the {L}obaye area. {N}o risk factor was clearly identify regarding the use of natural resources of the forest which include hunting, gathering and fishing... ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{FIEVRE} {HEMORRAGIQUE} ; {EPIDEMIOLOGIE} ; {SEROLOGIE} ; {PREVALENCE} ; {SEX} {RATIO} ; {SANG} ; {ECHANTILLONNAGE} ; {TEST} {ELISA} ; {PROJET} {DE} {RECHERCHE} ; {VIRUS} {EBOLA} ; {VIRUS} {MARBURG} ; {CENTRAFRIQUE} ; {LOBAYE} {REGION}},
  address = {{N}akhonpathom},
  publisher = {{M}ahidol {U}niversity},
  series = {},
  pages = {78  multigr.},
  year = {1997},
  URL = {https://www.documentation.ird.fr/hor/fdi:010015987},
}