@article{fdi:010015593,
  title = {{D}egradation and product analysis of caffeine and related dimethylxanthines by filamentous fungi},
  author = {{H}akil, {M}. and {D}enis, {S}. and {V}iniegra-{G}onzalez, {G}. and {A}ugur, {C}hristopher},
  editor = {},
  language = {{ENG}},
  abstract = {{T}wenty strains of filamentous fungi were tested for their ability to grow on a liquid medium containing caffeine (1,3,7-trimethylxanthine) as a sole nitrogen source. {S}even strains which were able to grow on caffeine belong to the #{A}spergillus$ and #{P}enicillium$ genuses. {T}hey all presented the same degradation pathways but varied in the efficiency by which degradation took place. {C}affeine was first demethylated in position 7 ; this lead to the formation of theophylline (1,3-dimethylxanthine). {T}his compound was next demethylated in position 1 to give 3-methylxanthine. {A}ll these strains were also able to grow on theophylline, theobromine (3,7-dimethylxanthine), and paraxanthine (1,7-dimethylxanthine) as a sole nitrogen source. {A}ll degradation intermediates detected were methylxanthines. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{FERMENTATION} ; {CHAMPIGNON} ; {CAFEINE} ; {BIODEGRADATION} ; {MILIEU} {DE} {CULTURE} ; {METABOLISME}},
  booktitle = {},
  journal = {{E}nzyme and {M}icrobial {T}echnology},
  volume = {22},
  numero = {},
  pages = {355--359},
  ISSN = {0141-0229},
  year = {1998},
  DOI = {10.1016/{S}0141-0229(97)00205-6},
  URL = {https://www.documentation.ird.fr/hor/fdi:010015593},
}