@article{fdi:010015465,
  title = {{G}enetic differentiation of {A}nopheles gambiae populations from {E}ast and {W}est {A}frica : comparison of microsatellite and allozyme loci},
  author = {{L}ehmann, {T}. and {H}awley, {W}.{A}. and {K}amau, {L}. and {F}ontenille, {D}idier and {S}imard, {F}r{\'e}d{\'e}ric and {C}ollins, {F}.{H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{G}enetic variation of #{A}nopheles gambiae$ was analysed to assess interpopulation divergence over a 6000 km distance using short tandem repeat (microsatellite) loci and allozyme loci. {D}ifferentiation of populations from {K}enya and {S}enegal measured by allele length variation at five microsatellite loci was compared with estimates calculated from published data on six allozyme loci ({M}iles, 1978). {T}he average {W}right's {F}({ST}) of microsatellite loci (0.016) was lower than that of allozymes (0.036). {S}latkin's {R}({ST}) values for microsatellite loci were generally higher than their {F}({ST}) values, but the average {R}({ST}) value was virtually identical (0.036) to the average allozyme {F}({ST}). {T}hese low estimates of differentiation correspond to an effective migration index ({N}m) larger than 3, suggesting that gene flow across the continent is only weakly restricted. {P}olymorphism of microsatellite loci was significantly higher than that of allozymes, probably because the former experience considerably higher mutation rates. {T}hat microsatellite loci did not measure greater interpopulation divergence than allozyme loci suggested constraints on microsatellite evolution. {A}lternatively, extensive mosquito dispersal, aided by human transportation during the last century, better explains the low differentiation and the similarity of estimates derived from both types of genetic markers. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{PALUDISME} ; {VECTEUR} ; {GENETIQUE} {DE} {POPULATION} ; {POLYMORPHISME} {GENETIQUE} ; {POLYMORPHISME} {ENZYMATIQUE} ; {ALLELE} ; {ETUDE} {COMPARATIVE} ; {GENETIQUE} {MOLECULAIRE} ; {ALLOZYME} ; {MICROSATELLITE} ; {AFRIQUE} {DE} {L}'{EST} ; {AFRIQUE} {DE} {L}'{OUEST} ; {KENYA} ; {SENEGAL}},
  booktitle = {},
  journal = {{H}eredity},
  volume = {77},
  numero = {},
  pages = {192--208},
  ISSN = {0018-067{X}},
  year = {1996},
  DOI = {10.1038/hdy.1996.124},
  URL = {https://www.documentation.ird.fr/hor/fdi:010015465},
}