@article{fdi:010015463, title = {{S}imian immunodeficiency virus infection in a patas monkey ({E}rythrocebus patas) : evidence for cross-species transmission from african green monkeys ({C}ercopithecus aethiops sabaeus) in the wild}, author = {{B}ibollet-{R}uche, {F}r{\'e}d{\'e}ric and {G}alat {L}uong, {A}nh and {C}uny, {G}{\'e}rard and {S}arni-{M}anchado, {P}ascale and {G}alat, {G}{\'e}rard and {D}urand, {J}.{P}. and {P}ourrut, {X}avier and {V}eas, {F}rancisco}, editor = {}, language = {{ENG}}, abstract = {{S}ocio-ethological studies on troops of {A}frican green monkeys ({AGM}s) (#{C}ercopithecus aethiops sabaeus$) and patas monkeys (#{E}rythrocebus patas$) in {S}enegal have documented physical contacts between these two species. {E}levated simian immunodeficiency virus ({SIV}) seroprevalence rates have been reported for the different {AGM} subspecies. {W}e report here the extent to which patas monkeys are infected and compare the relatedness of the viruses isolated from these two different species. {A}mong the 85 {AGM}s and 54 patas monkeys studied, 47% and 7.5%, respectively, had antibodies that cross-reacted with {HIV}-2 envelope proteins. {F}rom two {AGM}s a virus was isolated. {F}rom the patas monkeys, virus isolation was generally not possible, but from one animal that was ill a virus designated pam{G}31 was amplified by {PCR}. {I}n addition, for the two {SIV}agm isolates, an 830 bm region spanning the env and nef genes was amplified and sequenced. {C}omparisons of sequences from the env/nef region revealed 80% identity between pam{G}31 and {SIV}agm isolates from {AGM}s of the #sabaeus$ subspecies, and 94% identity between the two {SIV}agm isolates. {P}hylogenetic analysis showed that pam{G}31 belongs to the {SIV}agm #sabaeus$ subgroup. {T}his is the first report of a lentiviral infection in a patas monkey. {T}he close genetic relatedness between pam{G}31 and {SIV}agm #sabaeus$ viruses is a strong argument in favour of cross-species transmission of {SIV} between {AGM}s and patas monkeys in the wild. {F}or these reasons, we propose to refer to this patas virus as {SIV}agm-pam{G}31. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{VIRUS} ; {SEROLOGIE} ; {ISOLEMENT} ; {ANTICORPS} ; {TECHNIQUE} {PCR} ; {GENE} ; {PHYLOGENIE} ; {PREVALENCE} ; {TRANSMISSION} ; {RELATION} {INTERSPECIFIQUE} ; {SIV}.{VIRUS} {IMMUNODEFICIENCE} {SIMIENNE} ; {VIH} ; {SENEGAL}}, booktitle = {}, journal = {{J}ournal of {G}eneral {V}irology}, volume = {17}, numero = {}, pages = {773--781}, ISSN = {0001-3637}, year = {1996}, DOI = {10.1099/0022-1317-77-4-773}, URL = {https://www.documentation.ird.fr/hor/fdi:010015463}, }