@inproceedings{fdi:010013192,
  title = {{C}ontinuous enzymes and fungal metabolites production in solid state fermentation using a counter-current reactor},
  author = {{R}oussos, {S}evastianos and {P}yle, {D}.{L}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}his work presents the continuous production of fungal biomass and enzymes by solid state fermentation ({SSF}) in a counter-current reactor adapted for this purpose. {P}re-germinated conidia of #{A}spergillus niger$ were used as an inoculum and sugarcane bagasse, embedded with a nutritive solution, was the solid support. {T}he solids residence time distribution ({RTD}) was carried out by feeding one impulse of blue-coloured humidified bagasse and this {RTD} was fixed at 20 hours. {T}his study demonstrated that the values of the measured parameters (p{H}, moisture, biomass, glucoamylase production) were similar to those reported for batch {SSF} using the same solid support and micro-organism. {A} marked increase in biomass occurred from the progressive compartment (from compartment no.1 to no.9) into the reactor and the enzyme production was important (40 {IU}/g dry exit solids). {N}o mycelium damage or sporulation was observed. {T}he above results confirmed that the continuous production of enzymes by {SSF} under no sterile conditions was successful. {I}noculation with pre-germinated conidia shortened the processing time and allowed control of the age of the mycelium in each compartment. {A}eration was accomplished by natural convection and moisture content had to be controlled. {T}his process can be applied to the continuous production of fungal biomass and metabolites in {SSF} with industrial applications using environmentally friendly biotechnology. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{FERMENTATION} {EN} {MILIEU} {SOLIDE} ; {MILIEU} {DE} {CULTURE} ; {PRODUCTION} {INDUSTRIELLE} ; {MICROORGANISME} ; {CHAMPIGNON} ; {ENZYME} ; {GERMINATION} ; {FERMENTEUR} {DE} {LABORATOIRE} ; {BAGASSE} ; {MYCELIUM} ; {GLUCOAMYLASE}},
  numero = {98-1},
  pages = {21--35 multigr.},
  booktitle = {{I}nternational training course on solid state fermentation},
  year = {1998},
  URL = {https://www.documentation.ird.fr/hor/fdi:010013192},
}