@article{fdi:010008052,
  title = {{E}ffect of gametocyte sex ratio on infectivity of {P}lasmodium falciparum to {A}nopheles gambiae},
  author = {{R}obert, {V}incent and {R}ead, {A}.{F}. and {E}ssong, {J}. and {T}chuinkam, {T}. and {M}ulder, {B}. and {V}erhave, {J}.{P}. and {C}arnevale, {P}ierre},
  editor = {},
  language = {{ENG}},
  abstract = {{I}nsectary-reared #{A}nopheles gambiae$ were experimentally fed with the blood of 90 naturally infected human volunteers carrying gametocytes of #{P}lasmodium falciparum$. {A}t least one mosquito was successfully infected in 74 % of experiments. {T}he probability that a gametocyte carrier was infective, the probability that a mosquito became infected, and the number of oocysts harboured were related to gametocyte density. {T}he mean proportion of male gametocytes was 0.217 (i.e., 3.6 females for every male). {S}ex ratios differed significantly between gametocyte carriers. {V}ariation in sex ratio was not related to the probability that a gametocyte carrier was infective. {A}mong infective people whose sex ratio estimates were based on a reasonable number of gametocytes, sex ratio significantly predicted the proportion of infected mosquitoes and mean oocyst load, with infectivity rising as the proportion of male gametocytes increased towards 50 %. {T}here was no indication that infectivity reached a peak at some intermediate sex ratio, as would be expected if random mating of gametes was the primary determinant of fertilization success. {T}hese results raise 2 interesting questions : why should higher sex ratios be more infective, and why is the observed population sex ratio lower than that which produced the greatest infectivity ? ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{PALUDISME} ; {VECTEUR} ; {INFESTATION} ; {AGENT} {PATHOGENE} ; {GAMETOGENESE} ; {CYCLE} {DE} {DEVELOPPEMENT} ; {SEX} {RATIO} ; {CAMEROUN} ; {YAOUNDE}},
  booktitle = {},
  journal = {{T}ransactions of the {R}oyal {S}ociety of {T}ropical {M}edecine and {H}ygiene},
  volume = {90},
  numero = {6},
  pages = {621--624},
  ISSN = {0035-9203},
  year = {1996},
  DOI = {10.1016/{S}0035-9203(96)90408-3},
  URL = {https://www.documentation.ird.fr/hor/fdi:010008052},
}