@inproceedings{fdi:010007008,
  title = {{G}eographic structure of {A}nopheles gambiae (savanna form) in {A}frica based on microsatellite, allozyme and mitochondrial loci},
  author = {{L}ehmann, {T}. and {H}awley, {W}.{A}. and {B}esansky, {N}.{J}. and {F}ontenille, {D}idier and {S}imard, {F}. and {F}ahey, {T}.{G}. and {K}amau, {L}. and {C}ollins, {F}.{H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he genetic structure of #{A}nopheles gambiae$ populations representing extreme geographic scales was studied based on several genetic markers. {T}hese scales included houses within a village, villages up to 50km apart, and countries 6000 km away. {T}he following questions were answered : (1) {A}re mosquitoes in a house more related genetically to each other than mosquitoes in different houses ? (2) {W}hat degree of genetic differentiation occurs on these geographic scales ? and (3) {H}ow consistent are the results obtained by separate genetic markers ? {N}o differentiation was detected among houses by {FST}, {RST} and the band sharing index tests applied to the 5 microsatellite loci. {L}ikewise, indices of kinship based on mt{DNA} haplotypes in houses were even lower than in the pooled sample. {T}hus, the hypothesis that mosquitoes in a house are more related genetically was rejected. {N}o subdivision of the gene pool among 4 villages in western {K}enya was detected by {FST} or {RST} based on the 5 microsatellite loci. {L}ikewise, estimates of haplotype divergence of mt{DNA} between these villages were not higher than the within population estimates. {S}ignificant divergence between populations from {K}enya and {S}enegambia was detected by 3 of the 5 microsatellite loci (average {W}right's {FST} was 0.016 and average {S}latkin's {RST} was 0.036) and by 2 of 6 allozyme loci (average {FST} was 0.036, calculated based on {M}iles, 1978). {T}hese values are surprisingly low and correspond to an effective migration index ({N}m) larger than 3, suggesting gene flow across the continent is only weakly restricted. {T}he concordance between results based on microsatellite loci and mt{DNA} at the microgeographic levels, and between the allozyme's {FST} and the microsatellite's {RST} at the macrogeographical level attested for this description of the population structure. ({R}{\'e}sum{\'e} d'auteur)},
  keywords = {{PALUDISME} ; {VECTEUR} ; {REPARTITION} {GEOGRAPHIQUE} ; {GENETIQUE} {DE} {POPULATION} ; {SPECIATION} ; {POLYMORPHISME} {ENZYMATIQUE} ; {AFRIQUE}},
  volume = {55},
  numero = {2},
  pages = {241--242},
  booktitle = {{P}rogram and abstract of the 45th annual {M}eeting of the {A}merican {S}ociety of {T}ropical {M}edicine and {H}ygiene},
  year = {1996},
  URL = {https://www.documentation.ird.fr/hor/fdi:010007008},
}