Lehmann T., Hawley W.A., Besansky N.J., Fontenille Didier, Simard F., Fahey T.G., Kamau L., Collins F.H. (1996). Geographic structure of Anopheles gambiae (savanna form) in Africa based on microsatellite, allozyme and mitochondrial loci. In :
Program and abstract of the 45th annual Meeting of the American Society of Tropical Medicine and Hygiene. American Journal of Tropical Medicine and Hygiene, 55 (2), p. 241-242. Annual Meeting of the American Society of Tropical Medicine and Hygiene, 45., Baltimore (USA), 1996/12/1-5.
Titre du document
Geographic structure of Anopheles gambiae (savanna form) in Africa based on microsatellite, allozyme and mitochondrial loci
Année de publication
1996
Type de document
Colloque
Auteurs
Lehmann T., Hawley W.A., Besansky N.J., Fontenille Didier, Simard F., Fahey T.G., Kamau L., Collins F.H.
In
Program and abstract of the 45th annual Meeting of the American Society of Tropical Medicine and Hygiene
Source
American Journal of Tropical Medicine and Hygiene, 1996,
55 (2), p. 241-242
Colloque
Annual Meeting of the American Society of Tropical Medicine and Hygiene, 45., Baltimore (USA), 1996/12/1-5
The genetic structure of Anopheles gambiae populations representing extreme geographic scales was studied based on several genetic markers. These scales included houses within a village, villages up to 50km apart, and countries 6000 km away. The following questions were answered : (1) Are mosquitoes in a house more related genetically to each other than mosquitoes in different houses ? (2) What degree of genetic differentiation occurs on these geographic scales ? and (3) How consistent are the results obtained by separate genetic markers ? No differentiation was detected among houses by FST, RST and the band sharing index tests applied to the 5 microsatellite loci. Likewise, indices of kinship based on mtDNA haplotypes in houses were even lower than in the pooled sample. Thus, the hypothesis that mosquitoes in a house are more related genetically was rejected. No subdivision of the gene pool among 4 villages in western Kenya was detected by FST or RST based on the 5 microsatellite loci. Likewise, estimates of haplotype divergence of mtDNA between these villages were not higher than the within population estimates. Significant divergence between populations from Kenya and Senegambia was detected by 3 of the 5 microsatellite loci (average Wright's FST was 0.016 and average Slatkin's RST was 0.036) and by 2 of 6 allozyme loci (average FST was 0.036, calculated based on Miles, 1978). These values are surprisingly low and correspond to an effective migration index (Nm) larger than 3, suggesting gene flow across the continent is only weakly restricted. The concordance between results based on microsatellite loci and mtDNA at the microgeographic levels, and between the allozyme's FST and the microsatellite's RST at the macrogeographical level attested for this description of the population structure. (Résumé d'auteur)
Plan de classement
Répartition et bioécologie des anophèles [052ANOPAL02]
Descripteurs
PALUDISME ; VECTEUR ; REPARTITION GEOGRAPHIQUE ; GENETIQUE DE POPULATION ; SPECIATION ; POLYMORPHISME ENZYMATIQUE
Description Géographique
AFRIQUE
Localisation
Fonds IRD [F B010007008] ;
Dakar
;
Montpellier (Centre IRD)
Identifiant IRD
fdi:010007008
