%0 Book Section %9 OS CH : Chapitres d'ouvrages scientifiques %A Gunasekaran, P. %A Augur, Christopher %A Viniegra-Gonzalez, G. %A Favela-Torres, E. %T Approaches towards improvement of microbial strains used in solid state fermentation %B Fronteras in biotecnologia y bioingenieria %C Mexico %D 1996 %E Galindo, E. %L fdi:010006836 %G ENG %I Sociedad Mexicana de Biotecnologia y Bioingenieria %@ 968-7735-00-7 %K FERMENTATION EN MILIEU SOLIDE ; MICROORGANISME ; SOUCHE ; AMELIORATION GENETIQUE %P 359-364 %U https://www.documentation.ird.fr/hor/fdi:010006836 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_45-46/010006836.pdf %W Horizon (IRD) %X The low water activity, the complex nature of the support and/or substrate, the concentation of substrates used and products formed, and the heterogeneity within the system, influence the growth and physiology of the microbial strains used in solid state fermentation (SSF). As a result, the quality and quantity of the products formed from SSF processes significantly differ from those of submerged fermentation (SmF). Some strains that performed well in SmF processes do not perform efficiently in SSF process. Therefore, it is necessary to maximize the potential of the organism through genetic manipulation to suit the SSF process. Some of the desirable characteristics to be considered for the improvement of the microbial strains for SSF are : tolerance to low water activity and elevated temperature, deregulation of stringent metabolic controls, insensitivity to concentrations of the substrates and products. The genes responsible for counteracting the effect of increased osmotic condition, temperature, carbon and nitrogen catabolite repression are to be identified in the SSF organisms. They may be suitable manipulated in the producers or/and may be transferred to the producer organism. (Résumé d'auteur) %B Congreso Nacional de Biotecnologia y Bioingenieria %8 1995/09/10-14 %$ 084FERMEN