@incollection{fdi:010006836, title = {{A}pproaches towards improvement of microbial strains used in solid state fermentation}, author = {{G}unasekaran, {P}. and {A}ugur, {C}hristopher and {V}iniegra-{G}onzalez, {G}. and {F}avela-{T}orres, {E}.}, editor = {}, language = {{ENG}}, abstract = {{T}he low water activity, the complex nature of the support and/or substrate, the concentation of substrates used and products formed, and the heterogeneity within the system, influence the growth and physiology of the microbial strains used in solid state fermentation ({SSF}). {A}s a result, the quality and quantity of the products formed from {SSF} processes significantly differ from those of submerged fermentation ({S}m{F}). {S}ome strains that performed well in {S}m{F} processes do not perform efficiently in {SSF} process. {T}herefore, it is necessary to maximize the potential of the organism through genetic manipulation to suit the {SSF} process. {S}ome of the desirable characteristics to be considered for the improvement of the microbial strains for {SSF} are : tolerance to low water activity and elevated temperature, deregulation of stringent metabolic controls, insensitivity to concentrations of the substrates and products. {T}he genes responsible for counteracting the effect of increased osmotic condition, temperature, carbon and nitrogen catabolite repression are to be identified in the {SSF} organisms. {T}hey may be suitable manipulated in the producers or/and may be transferred to the producer organism. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{FERMENTATION} {EN} {MILIEU} {SOLIDE} ; {MICROORGANISME} ; {SOUCHE} ; {AMELIORATION} {GENETIQUE}}, booktitle = {{F}ronteras in biotecnologia y bioingenieria}, numero = {}, pages = {359--364}, address = {{M}exico}, publisher = {{S}ociedad {M}exicana de {B}iotecnologia y {B}ioingenieria}, series = {}, year = {1996}, ISBN = {968-7735-00-7}, URL = {https://www.documentation.ird.fr/hor/fdi:010006836}, }