Gantier J.C., Fournet Alain, Munos M.H., Hocquemiller R. (1996). The effect of some 2-substituted quinolines isolated from Galipea longiflora on Plasmodium vinckei petteri infected mice. Planta Medica, 62, p. 285-286. ISSN 0032-0943.
Titre du document
The effect of some 2-substituted quinolines isolated from Galipea longiflora on Plasmodium vinckei petteri infected mice
Année de publication
1996
Type de document
Article
Auteurs
Gantier J.C., Fournet Alain, Munos M.H., Hocquemiller R.
Source
Planta Medica, 1996,
62, p. 285-286 ISSN 0032-0943
We have evaluated the in vivo antiplasmodial activity of six 2-substituted quinolines and a total alkaloidal extract of Galipea longiflora. BALB/c mice infected with Plasmodium vinckei petteri were treated orally at single dose of 50 mg/kg with quinolines or extract. Contrary to the previous results obtained with the Leishmania murine infection, 2-n-pentylquinoline showed activity against P. vinckei petteri. This result seems to confirm the antimalarial efficacy of infused stem bark of G. longiflora. (Résumé d'auteur)
