@article{fdi:010006219, title = {{M}other-to-child transmission of human {T}-cell lymphotropic virus types {I} and {II} ({HTLV}-{I}/{II}) in {G}abon : a prospective follow-up of 4 years}, author = {{N}yambi, {P}.{N}. and {V}ille, {Y}. and {L}ouwagie, {J}. and {B}edjabaga, {I}. and {G}lowaczower, {E}. and {P}eeters, {M}artine and {K}erouedan, {D}. and {D}azza, {M}.{C}. and {L}arouz{\'e}, {B}. and {V}an der {G}roen, {G}. and {D}elaporte, {E}ric}, editor = {}, language = {{ENG}}, abstract = {{F}or 4 years, we determined the mode and risk of mother-to-child transmission of {HTLV}-{I} in a prospective cohort of 34 children born to seropositive mothers in {F}ranceville, {G}abon. {W}e also determined the prevalence of antibodies to {HTLV}-{I}/{II} in siblings born to seropositive mothers. {A}ntibodies to {HTLV}-{I}/{II} were detected by {W}estern blot, and the proviral {DNA} was detected by the polymerase chain reaction ({PCR}). {T}he risk of seroconversion to anti-{HTLV}-{I} for the 4 years of follow-yp was 17.5 %. {A}nti-{HTLV}-{I}/{II} and proviral {DNA} were only detected after age 18 months. {W}e observed a seroprevalence rate of 15 % among the siblings born to {HTLV}-{I}/{II} seropositive mothers. {F}urthermore, we report a case of mother-to-child transmission of {HTLV}-{II} infection in a population of {HTLV}-{II}-infected pregnant women that is emerging in {G}abon. {T}he lack of detection of {HTLV}-{I}/{II} proviral {DNA} in cord blood and amniotic fluid and, furthermore, the late seroconversion observed in the children indirectly indicate that mother-to-child transmission occured postnatally, probably through breast milk. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{SIDA} ; {GROSSESSE} ; {EPIDEMIOLOGIE} ; {TRANSMISSION} ; {FOETUS} ; {NOURRISSON} ; {SEROLOGIE} ; {ADN} ; {LEUCEMIE} ; {LYMPHOME} ; {VIRUS} {HTLV}-1 ; {VIRUS} {HTLV}-2 ; {PCR}. {POLYMERASE} {CHAIN} {REACTION} ; {GABON}}, booktitle = {}, journal = {{J}ournal of {A}cquired {I}mmune {D}eficiency {S}yndromes and {H}uman {R}etrovirology}, volume = {12}, numero = {2}, pages = {187--192}, ISSN = {0894-9255}, year = {1996}, URL = {https://www.documentation.ird.fr/hor/fdi:010006219}, }