@article{PAR00015080, title = {{A}natomical and technical factors influence the rate of in-stent restenosis following carotid artery stenting for the treatment of post-carotid endarterectomy stenosis}, author = {{G}audry, {M}. and {B}artoli, {J}. {M}. and {B}al, {L}. and {G}iorgi, {R}och and {D}e {M}asi, {M}. and {M}agnan, {P}. {E}. and {P}iquet, {P}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground {C}arotid arterystenting ({CAS}) has been advocated as an alternative to redo surgery for the treatment of post-carotid endarterectomy({CEA}) stenosis. {T}his study analyzed the efficacy of {CAS} for post-{CEA} restenosis, focusing on an analysis of technical and anatomical predictive factors for in-stent restenosis. {M}ethods {W}e performed a retrospective monocentric study. {W}e included all patients who underwent {CAS} for post-{CEA} restenosis at our institution from {J}uly 1997 to {N}ovember 2013. {T}he primary endpoints were the technical success, the presence of in-stent restenosis > 50% or occlusion, either symptomatic or asymptomatic, during the follow-up period, and risk factors for restenosis. {T}he secondary endpoints were early and late morbidity and mortality ({TIA}, stroke, myocardial infarction, or death). {R}esults {A} total of 153 {CAS} procedures were performed for post-{CEA} restenosis, primarily because of asymptomatic lesions (137/153). {T}he technical success rate was 98%. {T}he 30-day perioperative stroke and death rate was 2.6% (two {TIA}s and two minor strokes), and rates of 2.2% (3/137) and 6.2% (1/16) were recorded for asymptomatic and symptomatic patients, respectively. {T}he average follow-up time was 36 months (range, 6-171 months). {I}n-stent restenosis or occlusion was observed in 16 patients (10.6%). {S}ymptomatic restenosis was observed in only one patient. {W}e found that young age ({P} = 0.002), stenosis > 85% ({P} = 0.018), and a lack of stent coverage of the common carotid artery({P} = 0.006) were independent predictors of in-stent restenosis. {C}onclusion {W}e identified new risk factors for in-stent restenosis that were specific to this population, and we propose a technical approach that may reduce this risk.}, keywords = {}, booktitle = {}, journal = {{P}los {O}ne}, volume = {11}, numero = {9}, pages = {e0161716}, ISSN = {1932-6203}, year = {2016}, DOI = {10.1371/journal.pone.0161716}, URL = {https://www.documentation.ird.fr/hor/{PAR}00015080}, }