@article{PAR00014818,
  title = {{A}ortic function's adaptation in response to exercise-induced stress assessing by 1.5{T} {MRI} : a pilot study in healthy volunteers},
  author = {{B}al-{T}heoleyre, {L}. and {L}alande, {A}. and {K}ober, {F}. and {G}iorgi, {R}och and {C}ollart, {F}. and {P}iquet, {P}. and {H}abib, {G}. and {A}vierinos, {J}. {F}. and {B}ernard, {M}. and {G}uye, {M}. and {J}acquier, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}im {E}valuation of the aortic "elastic reserve" might be a relevant marker to assess the risk of aortic event. {O}ur aim was to compare regional aortic elasticity at rest and during supine bicycle exercise at 1.5 {T} {MRI} in healthy individuals. {M}ethods {F}ifteen volunteers (8 men), with a mean age of 29 (23-41) years, completed the entire protocol. {I}mages were acquired immediately following maximal exercise. {R}etrospective cine sequences were acquired to assess compliance, distensibility, maximum rates of systolic distension and diastolic recoil at four different locations: ascending aorta, proximal descending aorta, distal descending aorta and aorta above the coeliac trunk level. {S}egmental aortic pulse wave velocity ({PWV}) was assessed by through plane velocity-encoded {MRI}. {R}esults {E}xercise induced a significant decrease of aortic compliance and distensibility, and a significant increase of the absolute values of maximum rates of systolic distension and diastolic recoil at all sites (p<10-3). {A}t rest and during stress, ascending aortic compliance was statistically higher compared to the whole descending aorta (p <= 0.0007). {W}e found a strong correlation between the rate pressure product and aortic distensibility at all sites (r = - 0.6 to - 0.75 according to the site, p<10-4). {PWV} measured at the proximal and distal descending aorta increased significantly during stress (p = 0.02 and p = 0.008, respectively). {C}onclusion {A}ssessment of regional aortic function during exercise is feasible using {MRI}. {D}uring stress, aortic elasticity decreases significantly in correlation with an increase of the {PWV}. {F}urther studies are required to create thresholds for ascending aorta dysfunction among patients with aneurysms, and to monitor the impact of medication on aortic remodeling.},
  keywords = {},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {11},
  numero = {6},
  pages = {e0157704},
  ISSN = {1932-6203},
  year = {2016},
  DOI = {10.1371/journal.pone.0157704},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00014818},
}