@article{PAR00014817, title = {{T}he role of giant viruses of amoebas in humans}, author = {{C}olson, {P}. and {A}herfi, {S}. and {L}a {S}cola, {B}. and {R}aoult, {D}idier}, editor = {}, language = {{ENG}}, abstract = {{S}ince 2003, dozens of giant viruses that infect amoebas ({GVA}), including mimiviruses and marseilleviruses, have been discovered. {T}hese giants appear to be common in our biosphere. {F}rom the onset, their presence and possible pathogenic role in humans have been serendipitously observed or investigated using a broad range of technological approaches, including culture, electron microscopy, serology and various techniques based on molecular biology. {T}he link between amoeba! mimiviruses and pneumonia has been the most documented, with findings that fulfill several of the criteria considered as proof of viral disease causation. {R}egarding marseilleviruses, they have been mostly described in asymptomatic persons, and in a lymph node adenitis. {T}he presence and impact of {GVA} in humans undoubtedly deserve further investigation in medicine.}, keywords = {}, booktitle = {}, journal = {{C}urrent {O}pinion in {M}icrobiology}, volume = {31}, numero = {}, pages = {199--208}, ISSN = {1369-5274}, year = {2016}, DOI = {10.1016/j.mib.2016.04.012}, URL = {https://www.documentation.ird.fr/hor/{PAR}00014817}, }