%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Sharma, V.
%A Colson, P.
%A Pontarotti, P.
%A Raoult, Didier
%T Mimivirus inaugurated in the 21st century the beginning of a reclassification of viruses
%D 2016
%L PAR00014807
%G ENG
%J Current Opinion in Microbiology
%@ 1369-5274
%M ISI:000378454200005
%P 16-24
%R 10.1016/j.mib.2015.12.010
%U https://www.documentation.ird.fr/hor/PAR00014807
%V 31
%W Horizon (IRD)
%X Mimivirus and other giant viruses are visible by light microscopy and bona fide microbes that differ from other viruses and from cells that have a ribosome. They can be defined by: giant virion and genome sizes; their complexity, with the presence of DNA and mRNAs and dozens or hundreds of proteins in virions; the presence of translation-associated components; a mobilome including (pro)virophages (and a defence mechanism, named MIMIVIRE, against them) and transpovirons; their monophyly; the presence of the most archaic protein motifs they share with cellular organisms but not other viruses; a broader host range than other viruses. These features show that giant viruses are specific, autonomous, biological entities that warrant the creation of a new branch of microbes.
%$ 052 ; 020 ; 084