@article{PAR00013947,
  title = {{A}ntibiotic susceptibility of {N}eochlamydia hartmanellae and {P}arachlamydia acanthamoebae in amoebae},
  author = {{V}ouga, {M}. and {D}iabi, {H}. and {B}oulos, {A}. and {B}aud, {D}. and {R}aoult, {D}idier and {G}reub, {G}.},
  editor = {},
  language = {{ENG}},
  abstract = {{P}arachlamydia acanthamoebae and {N}eochlamydia hartmanellae are {C}hlamydia-related bacteria naturally infecting free-living amoebae. {T}hese strict intracellular bacteria might represent emerging pathogens. {R}ecent studies report an association with lower respiratory tract infections, especially with pneumonia where they have been identified as a potential causative agent in 1-2% of cases. {I}n this study, we defined the antibiotic susceptibility of {N}. hartmanellae, two strains of {P}. acanthamoebae and two yet unclassified {P}arachlamydiaceae strains using a quantitative approach. {W}e confirmed the results obtained earlier for {P}. acanthamoebae strain {B}n9 in an observational study. {M}acrolides ({MIC}s < 0.06-0.5 mu g/ml), rifampicin ({MIC}s 0.25-2) and doxycycline (2-4 mu g/ml) were active against {P}. acanthamoebae strains and {N}eochlamydia. {A}ll strains were resistant to amoxicillin, ceftriaxone and imipenem ({MIC} >= 32 mu g/ml). {S}imilarly to other {C}hlamydia-related bacteria, all investigated {P}arachlamydiaceae were resistant to quinolones ({MIC}s >= 16 mu g/ml). {T}herefore, we recommend a treatment with macrolides for {P}arachlamydia-associated pneumonia.},
  keywords = {{P}arachlamydiaceae ; {A}ntibiotic ; {P}neumonia ; {C}hlamydia ; {I}ntracellular bacteria},
  booktitle = {},
  journal = {{M}icrobes and {I}nfection},
  volume = {17},
  numero = {11-12},
  pages = {761--765},
  ISSN = {1286-4579},
  year = {2015},
  DOI = {10.1016/j.micinf.2015.08.002},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00013947},
}