@article{PAR00013934,
  title = {{V}irus isolation, genetic characterization and seroprevalence of {T}oscana virus in {A}lgeria},
  author = {{A}lkan, {C}. and {A}llal-{I}khlef, {A}. {B}. and {A}lwassouf, {S}. and {B}aklouti, {A}. and {P}iorkowski, {G}. and de {L}amballerie, {X}avier and {I}zri, {A}. and {C}harrel, {R}. {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}oscana virus ({TOSV}; {B}unyaviridae, {P}hlebovirus) is transmitted by sandflies of the genus {P}hlebotomus in the {M}editerranean area. {O}ne strain of {TOSV} was isolated from a total of almost 23 000 sandflies collected in {K}abylia, {A}lgeria. {T}he complete genome was sequenced, and phylogenetic studies indicated that it was most closely related with {TOSV} strain from {T}unisia within lineage {A}, which also includes {I}talian, {F}rench and {T}urkish strains. {A} seroprevalence study performed on 370 sera collected from people living in the same area showed that almost 50% possessed neutralizing antibodies against {TOSV}, a rate much higher than that observed in {S}outhern {E}urope. {S}andfly species distribution in the study area suggests that the vector of {TOSV} in this region belongs to the subgenus {L}arroussius. {T}hese data support the rapid implementation of the diagnosis of {TOSV} in clinical microbiology laboratories to estimate the burden in patients presenting with neuroinvasive infections and febrile illness. {C}linical {M}icrobiology and {I}nfection ({C}) 2015 {E}uropean {S}ociety of {C}linical {M}icrobiology and {I}nfectious {D}iseases. {P}ublished by {E}lsevier {L}td. {A}ll rights reserved.},
  keywords = {{C}omplete genome sequencing ; microneutralization ; {P}hlebovirus ; seroprevalence ; {T}oscana virus ; vector-borne infection ; {ALGERIE}},
  booktitle = {},
  journal = {{C}linical {M}icrobiology and {I}nfection},
  volume = {21},
  numero = {11},
  pages = {{UNSP} 1040.e1},
  ISSN = {1198-743{X}},
  year = {2015},
  DOI = {10.1016/j.cmi.2015.07.012},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00013934},
}