@article{PAR00013735,
  title = {{G}onadal transcriptome analysis of wild contaminated female {E}uropean eels during artificial gonad maturation},
  author = {{B}aillon, {L}. and {O}ses, {J}. and {P}ierron, {F}. and du {C}olombier, {S}. {B}. and {C}aron, {A}. and {N}ormandeau, {E}. and {L}ambert, {P}. and {C}outure, {P}. and {L}abadie, {P}. and {B}udzinski, {H}. and {D}ufour, {S}ylvie and {B}ernatchez, {L}. and {B}audrimont, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{S}ince the early 1980s, the population of {E}uropean eels ({A}nguilla anguilla) has dramatically declined. {N}owadays, the {E}uropean eel is listed on the red list of threatened species ({IUCN} {R}ed {L}ist) and is considered as critically endangered of extinction. {P}ollution is one of the putative causes for the collapse of this species. {A}mong their possible effects, contaminants gradually accumulated in eels during their somatic growth phase (yellow eel stage) would be remobilized during their reproductive migration leading to potential toxic events in gonads. {T}he aim of this study was to investigate the effects of organic and inorganic contaminants on the gonad development of wild female silver eels. {F}emale silver eels from two sites with differing contamination levels were artificially matured. {T}ranscriptomic analyses by means of a 1000 candidate gene c{DNA} microarray were performed on gonads after 11 weeks of maturation to get insight into the mechanisms of toxicity of contaminants. {T}he transcription levels of several genes, that were associated to the gonadosomatic index ({GSI}), were involved in mitotic cell division but also in gametogenesis. {G}enes associated to contaminants were mainly involved in the mechanisms of protection against oxidative stress, in {DNA} repair, in the purinergic signaling pathway and in steroidogenesis, suggesting an impairment of gonad development in eels from the polluted site. {T}his was in agreement with the fact that eels from the reference site showed a higher gonad growth in comparison to contaminated fish.},
  keywords = {{A}nguilla anguilla ; {S}ilver stage ; {C}ontamination ; {G}onad development ; {T}ranscriptomic},
  booktitle = {},
  journal = {{C}hemosphere},
  volume = {139},
  numero = {},
  pages = {303--309},
  ISSN = {0045-6535},
  year = {2015},
  DOI = {10.1016/j.chemosphere.2015.06.007},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00013735},
}