@article{PAR00013370,
  title = {{T}ransmission potential of {R}ickettsia felis infection by {A}nopheles gambiae mosquitoes},
  author = {{D}ieme, {C}. and {B}echah, {Y}. and {S}ocolovschi, {C}. and {A}udoly, {G}. and {B}erenger, {J}. {M}. and {F}aye, {O}. and {R}aoult, {D}idier and {P}arola, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A} growing number of recent reports have implicated {R}ickettsia felis as a human pathogen, paralleling the increasing detection of {R}. felis in arthropod hosts across the globe, primarily in fleas. {H}ere {A}nopheles gambiae mosquitoes, the primary malarial vectors in sub-{S}aharan {A}frica, were fed with either blood meal infected with {R}. felis or infected cellular media administered in membrane feeding systems. {I}n addition, a group of mosquitoes was fed on {R}. felisinfected {BALB}/c mice. {T}he acquisition and persistence of {R}. felis in mosquitoes was demonstrated by quantitative {PCR} detection of the bacteria up to day 15 postinfection. {R}. felis was detected in mosquito feces up to day 14. {F}urthermore, {R}. felis was visualized by immunofluorescence in salivary glands, in and around the gut, and in the ovaries, although no vertical transmission was observed. {R}. felis was also found in the cotton used for sucrose feeding after the mosquitoes were fed infected blood. {N}atural bites from {R}. felisinfected {A}n. gambiae were able to cause transient rickettsemias in mice, indicating that this mosquito species has the potential to be a vector of {R}. felis infection. {T}his is particularly important given the recent report of high prevalence of {R}. felis infection in patients with "fever of unknown origin" in malaria-endemic areas.},
  keywords = {{R}ickettsia felis ; spotted fever ; {A}nopheles gambiae ; {AFRIQUE} {SUBSAHARIENNE}},
  booktitle = {},
  journal = {{P}roceedings of the {N}ational {A}cademy of {S}ciences of the {U}nited {S}tates of {A}merica},
  volume = {112},
  numero = {26},
  pages = {8088--8093},
  ISSN = {0027-8424},
  year = {2015},
  DOI = {10.1073/pnas.1413835112},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00013370},
}