@article{PAR00013358, title = {{I}nfluenza-attributable deaths in south-eastern {F}rance (1999 to 2010) : mortality predictions were undependable}, author = {{T}hiberville, {S}. {D}. and {G}audart, {J}. and {R}aoult, {D}idier and {C}harrel, {R}. {N}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {F}ollowing the 2009 influenza pandemic, several studies showed that the mortality pattern associated with the {A}({H}1{N}1) 2009 virus primarily affected children and young adults. {I}n this study, we aimed to estimate the influenza-attributable deaths during the periods from 1999 to 2010, in the {P}rovence-{A}lpes-{C}pte-d'{A}zur ({PACA}) region of south-eastern {F}rance in order to corroborate the hypothesis that (i) influenza-attributable deaths caused by {A}({H}1{N}1) 2009 strain were much lower than initially expected. {M}ethods: {I}n order to compare our results with published data, we used the same statistical model of an {A}ustrian team, using a {P}oisson model adjusted on co-circulating respiratory syncytial virus to explain the weekly mortality. {R}esults: {W}e assessed that 5.7 % of the respiratory deaths were attributable to influenza virus during the 2009-2010 pandemic season. {T}his mortality was lower than that observed during the ten preceding epidemic periods (13.8 % on average). {A}ge group-based analysis revealed that during the pandemic period, the groups under 65 had a systematically higher excess of respiratory mortality while the age group over 65 had a much lower mortality than during the seasonal epidemic seasons. {S}imilarly, among the less specific outcome (non violent and cardiovascular mortality) the age groups over 45 had higher excess of mortality during the seasonal epidemics than during the pandemic period. {C}onclusions: {S}ince most of the influenza mortality is commonly observed in the elderly group (> 65 year-old), the moderate elderly mortality during the 2009 pandemic period has impacted the total mortality, and has resulted in a reduced total mortality despite an increased mortality in the young age group. {D}espite using identical parameters and the same approach as in a previously published study using an {A}ustrian population sample, we observed a lower excess respiratory mortality in the south-eastern {F}rance than in {V}ienna. {T}hus, the pandemic virus caused less death than the epidemic viruses that circulated during the preceding years. {I}n contrast with catastrophic predictions made in the early phase of the pandemic, human lives were saved during the circulation period of {A}({H}1{N}1) 2009 virus, resulting in a lower overall mortality.}, keywords = {{I}nfluenza mortality ; {P}andemic influenza {A}({H}1{N}1)2009 ; {I}nfluenza ; attributable deaths ; {I}nfluenza in {F}rance ; {FRANCE}}, booktitle = {}, journal = {{BMC} {P}ublic {H}ealth}, volume = {15}, numero = {}, pages = {art. 539 [5 p.]}, ISSN = {1471-2458}, year = {2015}, DOI = {10.1186/s12889-015-1887-y}, URL = {https://www.documentation.ird.fr/hor/{PAR}00013358}, }