@article{PAR00013200,
  title = {{A}cquisition of extended-spectrum cephalosporin- and colistin-resistant {S}almonella enterica subsp enterica serotype {N}ewport by pilgrims during {H}ajj},
  author = {{O}laitan, {A}. {O}. and {D}ia, {N}. {M}. and {G}autret, {P}. and {B}enkouiten, {S}. and {B}elhouchat, {K}. and {D}rali, {T}. and {P}arola, {P}. and {B}rouqui, {P}. and {M}emish, {Z}. and {R}aoult, {D}idier and {R}olain, {J}. {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{G}atherings like the {H}ajj involving many people who travel from different parts of the world represent a risk for the acquisition and dissemination of infectious diseases. {I}n this study, acquisition of multidrugresistant ({MDR}) {S}almonella spp. in 2013 {H}ajj pilgrims from {M}arseille, {F}rance, was investigated. {I}n total, 267 rectal swabs were collected from 129 participants before their departure and after their return from the pilgrimage as well as during the pilgrimage from patients with diarrhoea. {S}amples were screened for the presence of {S}almonella using quantitative real-time {PCR} and culture. {W}hole-genome sequencing was performed to characterise one of the isolates, and the mechanism leading to colistin resistance was investigated. {S}ix post-{H}ajj samples and one sample collected during a diarrhoea episode in {H}ajj were positive for {S}almonella by real-time {PCR}, with five {S}almonella enterica belonging to several serotypes recovered by culture, whereas no pre-{H}ajj sample was positive. {T}wo of the isolates belonged to the epidemic {N}ewport serotype, were resistant to cephalosporins, gentamicin and colistin, and harboured the bla({CTX}-{M}-2) gene and a 12-nucleotide deletion in the pmr13 gene leading to colistin resistance. {T}his study shows that pilgrims acquired {S}almonella bacteria, including a novel {MDR} clone, during the {H}ajj pilgrimage. {T}his calls for more improved public health surveillance during {H}ajj because {S}almonella is one of the most common diarrhoea-causing bacteria worldwide. {T}herefore, returning pilgrims could disseminate {MDR} bacteria worldwide upon returning to their home countries.},
  keywords = {{T}ravel ; {D}iarrohoea ; {D}rug resistance ; {P}ublic health ; beta-{L}actamases ; {FRANCE} ; {ARABIE} {SAOUDITE}},
  booktitle = {},
  journal = {{I}nternational {J}ournal of {A}ntimicrobial {A}gents},
  volume = {45},
  numero = {6},
  pages = {600--604},
  ISSN = {0924-8579},
  year = {2015},
  DOI = {10.1016/j.ijantimicag.2015.01.010},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00013200},
}