@article{PAR00013082,
  title = {{I}solation, genetic characterization, and seroprevalence of {A}dana virus, a novel phlebovirus belonging to the {S}alehabad virus complex, in {T}urkey},
  author = {{A}lkan, {C}. and {A}lwassouf, {S}. and {P}iorkowski, {G}. and {B}ichaud, {L}. and {T}ezcan, {S}. and {D}incer, {E}. and {E}rgunay, {K}. and {O}zbel, {Y}. and {A}lten, {B}. and de {L}amballerie, {X}avier and {C}harrel, {R}. {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A} new phlebovirus, {A}dana virus, was isolated from a pool of {P}hlebotomus spp. ({D}iptera; {P}sychodidae) in the province of {A}dana, in the {M}editerranean region of {T}urkey. {G}enetic analysis based on complete coding of genomic sequences indicated that {A}dana virus belongs to the {S}alehabad virus species of the genus {P}hlebovirus in the family {B}unyaviridae. {A}dana virus is the third virus of the {S}alehabad virus species for which the complete sequence has been determined. {T}o understand the epidemiology of {A}dana virus, a seroprevalence study using microneutralization assay was performed to detect the presence of specific antibodies in human and domestic animal sera collected in {A}dana as well as {M}ersin province, located 147 km west of {A}dana. {T}he results demonstrate that the virus is present in both provinces. {H}igh seroprevalence rates in goats, sheep, and dogs support intensive exposure to {A}dana virus in the region, which has not been previously reported for any virus included in the {S}alehabad serocomplex; however, low seroprevalence rates in humans suggest that {A}dana virus is not likely to constitute an important public health problem in exposed human populations, but this deserves further studies. {IMPORTANCE} {U}ntil recently, in the genus {P}hlebovirus, the {S}alehabad virus species consisted of two viruses: {S}alehabad virus, isolated from sand flies in {I}ran, and {A}rbia virus, isolated from sand flies in {I}taly. {H}ere we present the isolation and complete genome characterization of the {A}dana virus, which we propose to be included in the {S}alehabad virus species. {T}o our knowledge, this is the first report of the isolation and complete genome characterization, from sand flies in {T}urkey, of a {S}alehabad virus-related phlebovirus with supporting seropositivity in the {M}editerranean, {A}egean, and {C}entral {A}natolia regions, where phleboviruses have been circulating and causing outbreaks. {S}alehabad species viruses have generally been considered to be a group of viruses with little medical or veterinary interest. {T}his view deserves to be revisited according to our results, which indicate a high animal infection rate of {A}dana virus and recent evidence of human infection with {A}dria virus in {G}reece.},
  keywords = {{TURQUIE} ; {ZONE} {MEDITERRANEENNE}},
  booktitle = {},
  journal = {{J}ournal of {V}irology},
  volume = {89},
  numero = {8},
  pages = {4080--4091},
  ISSN = {0022-538{X}},
  year = {2015},
  DOI = {10.1128/jvi.03027-14},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00013082},
}