@article{PAR00013080, title = {{C}an plant viruses cross the kingdom border and be pathogenic to humans ?}, author = {{B}alique, {F}. and {L}ecoq, {H}. and {R}aoult, {D}idier and {C}olson, {P}.}, editor = {}, language = {{ENG}}, abstract = {{P}hytoviruses are highly prevalent in plants worldwide, including vegetables and fruits. {H}umans, and more generally animals, are exposed daily to these viruses, among which several are extremely stable. {I}t is currently accepted that a strict separation exists between plant and vertebrate viruses regarding their host range and pathogenicity, and plant viruses are believed to infect only plants. {A}ccordingly, plant viruses are not considered to present potential pathogenicity to humans and other vertebrates. {N}otwithstanding these beliefs, there are many examples where phytoviruses circulate and propagate in insect vectors. {S}everal issues are raised here that question if plant viruses might further cross the kingdom barrier to cause diseases in humans. {I}ndeed, there is close relatedness between some plant and animal viruses, and almost identical gene repertoires. {M}oreover, plant viruses can be detected in non-human mammals and humans samples, and there are evidence of immune responses to plant viruses in invertebrates, non-human vertebrates and humans, and of the entry of plant viruses or their genomes into non-human mammal cells and bodies after experimental exposure. {O}verall, the question raised here is unresolved, and several data prompt the additional extensive study of the interactions between phytoviruses and non-human mammals and humans, and the potential of these viruses to cause diseases in humans.}, keywords = {}, booktitle = {}, journal = {{V}iruses-{B}asel}, volume = {7}, numero = {4}, pages = {2074--2098}, ISSN = {1999-4915}, year = {2015}, URL = {https://www.documentation.ird.fr/hor/{PAR}00013080}, }