%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Ka, M. B.
%A Gondois-Rey, F.
%A Ghigo, E.
%A Raoult, Didier
%A Olive, D.
%A Mege, J. L.
%T Imbalance of circulating lymphoid cells in Q fever endocarditis
%D 2015
%L PAR00013074
%G ENG
%J Pathogens and Disease
%@ 2049-632X
%K Q fever ; endocarditis ; flow cytometry ; lymphoid compartment
%M ISI:000353152200003
%N 2
%P ftu010
%R 10.1093/femspd/ftu010
%U https://www.documentation.ird.fr/hor/PAR00013074
%V 73
%W Horizon (IRD)
%X Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naive CD8(+) T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8(+) T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis.
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