Ka M. B., Gondois-Rey F., Ghigo E., Raoult Didier, Olive D., Mege J. L. (2015). Imbalance of circulating lymphoid cells in Q fever endocarditis. Pathogens and Disease, 73 (2), p. ftu010. ISSN 2049-632X.
Titre du document
Imbalance of circulating lymphoid cells in Q fever endocarditis
Ka M. B., Gondois-Rey F., Ghigo E., Raoult Didier, Olive D., Mege J. L.
Source
Pathogens and Disease, 2015,
73 (2), p. ftu010 ISSN 2049-632X
Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naive CD8(+) T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8(+) T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis.